Background Early accurate detection of all skin cancer types is essential to guide appropriate
management and to improve morbidity and survival. Melanoma and squamous cell …

Background Melanoma accounts for a small proportion of all skin cancer cases but is responsible
for most skin cancer‐related deaths. Early detection and treatment can improve survival…

Varicocele can be very easily diagnosed by physical examination and subsequently treated
when it is painful or associated with testicular hypotrophy. However, palpability of the …

Objective To measure the performance of smartphone applications that evaluate photographs
of skin lesions and provide the user with feedback about the likelihood of malignancy. …

PGE 2 is a well-known immunomodulator produced in the immune response by APCs, such
as dendritic cells (DCs), the most potent APC of the immune system. We investigated the …

Cytomegalovirus (CMV) infection is characterized by host immunosuppression and multiorganic
involvement. CMV-infected dendritic cells (DC) were recently shown to display reduced …

We investigated the production of IL-2, IFN-γ, IL-10 and IL-4 by PBMC from 24 patients with
SLE and 10 healthy individuals. Basal and mitogen-stimulated (lipopolysaccharide and …

Objective Cytotoxic T lymphocyte–mediated killing using granzyme B has recently been
proposed to be a preferential and selective source of autoantigens in systemic autoimmune …

In normal individuals, γδ T cells account for less than 6% of total peripheral T lymphocytes
and mainly express T-cell receptor (TCR) Vδ2-Vγ9 chains. We have previously observed a …

Low-grade, chronic inflammation has been associated with many diseases of aging, but the
mechanisms responsible for producing this inflammation remain unclear. Inflammasomes …