Objective Anti–citrullinated protein antibodies (ACPAs) are disease‐specific biomarkers in
rheumatoid arthritis (RA). More than 90% of IgG ACPAs harbor N‐linked glycans in the …

Objective. To determine the prevalence of anti-cyclic citrullinated peptide (anti-CCP) antibodies
in unaffected relatives of North American Native probands with rheumatoid arthritis (RA); …

Background Epigenetic mechanisms can integrate gene-environment interactions that mediate
disease transition from preclinical to clinically overt rheumatoid arthritis (RA). To better …

Objective To determine the incidence of inflammatory arthritis and autoantibody prevalence
in Indigenous North American people. Methods Unaffected relatives of Indigenous North …

Objective. To describe differences in phenotype and outcomes in North American Native (NAN)
patients with rheumatoid arthritis (RA) followed prospectively and compared to white …

Objective. To examine reproductive history and rheumatoid arthritis (RA) risk in a highly
predisposed population of North American Natives (NAN) with unique fertility characteristics. …

Objective The pathogenetic mechanisms by which HLA-DRB1 alleles are associated with
anticitrullinated peptide antibody (ACPA)-positive rheumatoid arthritis (RA) are incompletely …

Recognition of the association between RA and PD on both a clinical and biologic level
may provide new opportunities for intervention that will modify the course of both of these …

Objective. The preclinical period of rheumatoid arthritis (RA) is characterized by the presence
of autoantibodies such as anticitrullinated protein antibodies (ACPA) and rheumatoid …

Objective Rheumatoid arthritis (RA) is prevalent in North American Native populations, with
a high frequency of multicase families and seropositivity in first‐degree relatives. This study …