Se ha descrito un nuevo síndrome inflamatorio multisistémico pediátrico vinculado a SARS-CoV-2.
Este cuadro presenta una expresividad clínica variable y se asocia a infección activa …

Background Familial Mediterranean fever, mevalonate kinase deficiency (also known as the
hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor receptor–associated …

Objective Mevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by
recurrent inflammatory episodes. This study was undertaken to describe the genotype, …

Background To our knowledge, the characteristics and burden of childhood arthritis have
never been studied on a worldwide basis. We aimed to investigate, with a cross-sectional study…

Objectives To develop data-driven criteria for clinically inactive disease on and off therapy
for juvenile dermatomyositis (JDM). Methods The Paediatric Rheumatology International …

Objectives This ongoing Phase-2, randomised, placebo-controlled, double-blind study
evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood-onset …

Background Juvenile idiopathic arthritis can be refractory to some or all treatment regimens,
therefore new medications are needed to treat this population. This trial assessed the …

Abatacept improves healthâ•’related quality of life, pain, sleep quality, and daily participation
in subjects with juvenile Page 1 Abatacept Improves Health-Related Quality of Life, Pain, …

Background Treatment options in patients with enthesitis-related arthritis (ERA) and juvenile
psoriatic arthritis (JPsA) are currently limited. This trial aimed to demonstrate the efficacy …

Objective. The main objective was to determine the 2-year clinical benefit and safety of
etanercept (ETN) in children with the juvenile idiopathic arthritis (JIA) categories of extended …