Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and …

…, H Dér, Z Sándor, G Lakos, L Muszbek, I Csipö… - The Journal of …, 2008 - jrheum.org
OBJECTIVE: Cardiovascular disease is a leading cause of mortality in rheumatoid arthritis (RA).
Endothelial dysfunction often precedes manifest atherosclerosis. We assessed …

[HTML][HTML] Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

…, A Csiszar, A Yabluchanskiy, S Conley, T Csipo… - Geroscience, 2020 - Springer
Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …

Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related …

…, Á Nyúl-Tóth, T Kiss, A Yabluchanskiy, T Csipo… - Geroscience, 2019 - Springer
Aging is associated with increased oxidative stress in vascular endothelial and smooth
muscle cells, which contribute to the development of a wide range of diseases affecting the …

[HTML][HTML] Comorbidities and increased mortality of COVID-19 among the elderly: A systematic review

…, M Fekete, Á Fehér, A Lehoczki, T Csípő… - Physiology …, 2022 - akjournals.com
Purpose The purpose of current review is to conduct a systematic overview of articles
published between 2019 and 2021 on the relationship of comorbidities and mortality due to …

Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD)

E Bodolay, Z Szekanecz, K Dévényi, L Galuska… - …, 2005 - academic.oup.com
Objective. Interstitial lung disease (ILD) may be a characteristic, often serious, manifestation
of mixed connective tissue disease (MCTD). In this retrospective study, the frequency and …

Characteristics of interstitial lung disease in SS-A positive/Jo-1 positive inflammatory myopathy patients

A Váncsa, I Csípő, J Németh, K Dévényi… - Rheumatology …, 2009 - Springer
The strongest predictive factor for the development of interstitial lung disease (ILD) in myositis
(IIM) patients is the presence of different antisynthetase antibodies. The aim of this study …

Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain

…, C Ahire, J DelFavero, A Yabluchanskiy, T Csipo… - Geroscience, 2020 - Springer
Age-related phenotypic changes of cerebromicrovascular endothelial cells lead to dysregulation
of cerebral blood flow and blood-brain barrier disruption, promoting the pathogenesis of …

Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain

…, R Nagaraja, F Yan, Q Tang, P Mukli, T Csipo… - Aging …, 2023 - Wiley Online Library
Chemotherapy‐induced cognitive impairment (“chemobrain”) is a frequent side‐effect in
cancer survivors treated with paclitaxel (PTX). The mechanisms responsible for PTX‐induced …

Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a …

…, S Tarantini, A Yabluchanskiy, T Csipo… - Geroscience, 2019 - Springer
Age-related impairment of angiogenesis likely has a critical role in cerebromicrovascular
rarefaction and development of vascular cognitive impairment and dementia (VCID) in the …

Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial …

…, S Tarantini, C Ahire, A Yabluchanskiy, T Csipo… - Geroscience, 2020 - Springer
Aging-induced structural and functional alterations of the neurovascular unit lead to
impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and …