The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype
IR Klein-Wieringa, M Kloppenburg… - Annals of the …, 2011 - ard.bmj.com
Objectives Obesity is a risk factor for the development of osteoarthritis (OA) in hands and
knees. Adipose tissue can secrete different adipokines with powerful immunomodulatory effects…
knees. Adipose tissue can secrete different adipokines with powerful immunomodulatory effects…
Inflammatory cells in patients with endstage knee osteoarthritis: a comparison between the synovium and the infrapatellar fat pad
IR Klein-Wieringa, BJE de Lange-Brokaar… - The Journal of …, 2016 - jrheum.org
Objective. To get a better understanding of inflammatory pathways active in the osteoarthritic
(OA) joint, we characterized and compared inflammatory cells in the synovium and the …
(OA) joint, we characterized and compared inflammatory cells in the synovium and the …
Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis
IR Klein‐Wieringa, MPM van der Linden… - Arthritis & …, 2011 - Wiley Online Library
Baseline serum adipokine levels predict radiographic progression in early rheumatoid
arthritis - Klein‐Wieringa - 2011 - Arthritis & Rheumatism - Wiley Online Library … Klein-Wieringa …
arthritis - Klein‐Wieringa - 2011 - Arthritis & Rheumatism - Wiley Online Library … Klein-Wieringa …
Adipocytes modulate the phenotype of human macrophages through secreted lipids
IR Klein-Wieringa, SN Andersen… - The Journal of …, 2013 - journals.aai.org
… Klein-Wieringa; … Klein-Wieringa … Klein-Wieringa, Stefan N. Andersen, Joanneke C.
Kwekkeboom, Martin Giera, Badelog JE de Lange-Brokaar, Gerjo JVM van Osch, Anne-Marie …
Kwekkeboom, Martin Giera, Badelog JE de Lange-Brokaar, Gerjo JVM van Osch, Anne-Marie …
Update on the treatment of nonsystemic juvenile idiopathic arthritis including treatment-to-target: is (drug-free) inactive disease already possible?
IR Klein-Wieringa, DMC Brinkman… - Current Opinion in …, 2020 - journals.lww.com
Remission can be achieved and sustained in (some) JIA patients, regardless of initial treatment.
Cornerstone principles in the management of nonsystemic JIA treatment are early start …
Cornerstone principles in the management of nonsystemic JIA treatment are early start …
[HTML][HTML] Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP)
AJ de Jong, IR Klein-Wieringa, SN Andersen… - Arthritis research & …, 2017 - Springer
Background Obesity is associated with the development and progression of osteoarthritis (OA).
Although the infrapatellar fat pad (IFP) could be involved in this association, due to its …
Although the infrapatellar fat pad (IFP) could be involved in this association, due to its …
Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis?
IR Klein-Wieringa, SN Andersen… - The Journal of …, 2014 - jrheum.org
Objective. To investigate whether high molecular weight adiponectin (hmwAPN) mediates
the associations of total adiponectin (totAPN) with radiographic progression in rheumatoid …
the associations of total adiponectin (totAPN) with radiographic progression in rheumatoid …
Inflammatory features of infrapatellar fat pad in rheumatoid arthritis versus osteoarthritis reveal mostly qualitative differences
AJ de Jong, IR Klein-Wieringa… - Annals of the …, 2018 - ard.bmj.com
Rheumatoid arthritis (RA) and osteoarthritis (OA) are characterised by joint destruction. In
both diseases, inflammation is implicated; however, RA is generally associated with more …
both diseases, inflammation is implicated; however, RA is generally associated with more …
[HTML][HTML] Synovial CD4+ T cells associate with pain in osteoarthritis: is there a role for fatty acids?
…, BJ De Lange-Brokaar, IR Klein-Wieringa… - Osteoarthritis and …, 2016 - oarsijournal.com
Purpose: Synovitis is associated with pain in patients with knee osteoarthritis (OA). However,
the cellular and molecular mechanisms underlying this association remain unclear. …
the cellular and molecular mechanisms underlying this association remain unclear. …
Adiponectin is a predictor for radiographic progression in early RA patients, independently of anti-CCP antibodies
IR Klein-Wieringa, MPM Van der Linden… - Annals of the …, 2011 - ard.bmj.com
Background and objectives Adipose tissue can secrete soluble mediators (adipokines) with
potent immune regulatory functions. Some adipokines have been previously associated with …
potent immune regulatory functions. Some adipokines have been previously associated with …