[HTML][HTML] The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: a systematic review and meta-analysis
Objective The assessment of health-related quality-of-life (HRQoL) in rheumatoid arthritis (RA)
is becoming increasingly common in both research and clinical practice. One of the most …
is becoming increasingly common in both research and clinical practice. One of the most …
Thromboembolism with Janus kinase (JAK) inhibitors for rheumatoid arthritis: how real is the risk?
IC Scott, SL Hider, DL Scott - Drug safety, 2018 - Springer
… Ian Scott is the statistician on a retrospective study entitled “… Scott will be receiving funding
for this work from Guy’s and St … Scott has received fees for consulting and giving educational …
for this work from Guy’s and St … Scott has received fees for consulting and giving educational …
The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta-analysis
Objectives. Our aim was to establish whether alcohol protects against RA development and
to determine whether this effect is influenced by alcohol dose, duration and serological …
to determine whether this effect is influenced by alcohol dose, duration and serological …
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some
of the most common human congenital abnormalities. Some of these defects originate from …
of the most common human congenital abnormalities. Some of these defects originate from …
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-ancestry
genetic research of RA promises to improve power to detect genetic signals, fine-…
genetic research of RA promises to improve power to detect genetic signals, fine-…
[HTML][HTML] Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl …
MI Uzel, IC Scott, H Babakhanlou-Chase… - Journal of Biological …, 2001 - ASBMB
Lysyl oxidase catalyzes the final enzymatic step required for collagen and elastin cross-linking
in extracellular matrix biosynthesis. Pro-lysyl oxidase is processed by procollagen C-…
in extracellular matrix biosynthesis. Pro-lysyl oxidase is processed by procollagen C-…
Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions …
IC Scott, IL Blitz, WN Pappano, Y Imamura… - Developmental …, 1999 - Elsevier
… 2, preliminary results show it to have proteolytic activity against other substrates such as
prolysyl oxidase (IC Scott, M. Uzel, PC Trackman, and DS Greenspan, unpublished results). …
prolysyl oxidase (IC Scott, M. Uzel, PC Trackman, and DS Greenspan, unpublished results). …
The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms
… Indeed we have found that cotransfection of ITF2 does not block the ability of HAND1 to
promote giant cell differentiation (IC Scott, unpublished results). Further work will be required to …
promote giant cell differentiation (IC Scott, unpublished results). Further work will be required to …
[HTML][HTML] Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
ES Cohen, IC Scott, JB Majithiya, L Rapley… - Nature …, 2015 - nature.com
In response to infections and irritants, the respiratory epithelium releases the alarmin interleukin
(IL)-33 to elicit a rapid immune response. However, little is known about the regulation …
(IL)-33 to elicit a rapid immune response. However, little is known about the regulation …
[HTML][HTML] Chromatin remodelling complex dosage modulates transcription factor function in heart development
Dominant mutations in cardiac transcription factor genes cause human inherited congenital
heart defects (CHDs); however, their molecular basis is not understood. Interactions …
heart defects (CHDs); however, their molecular basis is not understood. Interactions …