The pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The Pathogenesis of Rheumatoid Arthritis | NEJM Skip to main content NEJM Group Follow Us
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Cytokines in the pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - Nature Reviews Immunology, 2007 - nature.com
Cytokines regulate a broad range of inflammatory processes that are implicated in the
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options
…, F Crea, EC Thomson, IB McInnes - Cardiovascular …, 2020 - academic.oup.com
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents the
greatest medical challenge in decades. We provide a comprehensive review of the clinical …
greatest medical challenge in decades. We provide a comprehensive review of the clinical …
EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis
Objectives: To develop evidence-based EULAR recommendations for cardiovascular (CV)
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update
…, M Dougados, A Kerschbaumer, IB McInnes… - Annals of the …, 2020 - ard.bmj.com
Objectives To provide an update of the European League Against Rheumatism (EULAR)
rheumatoid arthritis (RA) management recommendations to account for the most recent …
rheumatoid arthritis (RA) management recommendations to account for the most recent …
EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 …
…, S Rollefstad, M Heslinga, IB McInnes… - Annals of the …, 2017 - ard.bmj.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have
increased cardiovascular disease (CVD) risk compared with the general population. In 2009, the …
increased cardiovascular disease (CVD) risk compared with the general population. In 2009, the …
Obesity is a risk factor for severe COVID-19 infection: multiple potential mechanisms
N Sattar, IB McInnes, JJV McMurray - Circulation, 2020 - Am Heart Assoc
Circulation. 2020; 142: 4–6. DOI: 10.1161/CIRCULATIONAHA. 120.047659 July 7, 2020 5
certain ethnicities, eg, Asians. 1 Asians often display lower cardiorespiratory fitness and carry …
certain ethnicities, eg, Asians. 1 Asians often display lower cardiorespiratory fitness and carry …
[HTML][HTML] Evidence that cytokines play a role in rheumatoid arthritis
FM Brennan, IB McInnes - The Journal of clinical …, 2008 - Am Soc Clin Investig
… In a phase II, placebo-controlled study, similar trends toward efficacy were observed (IB
McInnes, unpublished observations). This pathway remains under exploration in further clinical …
McInnes, unpublished observations). This pathway remains under exploration in further clinical …
Explaining how “high-grade” systemic inflammation accelerates vascular risk in rheumatoid arthritis
N Sattar, DW McCarey, H Capell, IB McInnes - Circulation, 2003 - Am Heart Assoc
There is intense interest in mechanisms whereby low-grade inflammation could interact with
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …
The JAK-STAT pathway: impact on human disease and therapeutic intervention
…, AV Villarino, M Gadina, IB McInnes… - Annual review of …, 2015 - annualreviews.org
The Janus kinase (JAK)–signal transducer of activators of transcription (STAT) pathway is
now recognized as an evolutionarily conserved signaling pathway employed by diverse …
now recognized as an evolutionarily conserved signaling pathway employed by diverse …