Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007–2008

Y Zhu, BJ Pandya, HK Choi - Arthritis & Rheumatism, 2011 - Wiley Online Library
Objective To estimate the prevalence of gout and hyperuricemia based on the latest nationally
representative sample of US men and women (National Health and Nutrition Examination …

Genetics of rheumatoid arthritis contributes to biology and drug discovery

…, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura… - Nature, 2014 - nature.com
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

Pathogenesis of gout

HK Choi, DB Mount, AM Reginato - Annals of internal medicine, 2005 - acpjournals.org
Researchers have recently made advances in defining the pathogenesis of gout, including
elucidating its risk factors and tracing the molecular mechanisms of renal urate transport and …

Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study

HK Choi, K Atkinson, EW Karlson… - Archives of internal …, 2005 - jamanetwork.com
Background Limited prospective information exists on the relation between obesity and
weight change and the risk of gout. Similarly, both hypertension and diuretic use have been …

Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta‐analysis of observational studies

JA Aviña‐Zubieta, HK Choi… - Arthritis Care & …, 2008 - Wiley Online Library
Objective To determine the magnitude of risk of cardiovascular mortality in patients with
rheumatoid arthritis (RA) compared with the general population through a meta‐analysis of …

[HTML][HTML] Purine-rich foods, dairy and protein intake, and the risk of gout in men

HK Choi, K Atkinson, EW Karlson… - New England Journal …, 2004 - Mass Medical Soc
Background Various purine-rich foods and high protein intake have long been thought to be
risk factors for gout. Similarly, the possibility that the consumption of dairy products has a …

Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study

HK Choi, MA Hernán, JD Seeger, JM Robins, F Wolfe - The Lancet, 2002 - thelancet.com
Background Methotrexate is the most frequent choice of disease-modifying antirheumatic
therapy for rheumatoid arthritis. Although results of studies have shown the efficacy of such …

Alcohol intake and risk of incident gout in men: a prospective study

HK Choi, K Atkinson, EW Karlson, W Willett, G Curhan - The Lancet, 2004 - thelancet.com
Background The association between alcohol consumption and risk of gout has been
suspected since ancient times, but has not been prospectively confirmed. Additionally, potential …

Intake of purine‐rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey

HK Choi, S Liu, G Curhan - … Journal of the American College of …, 2005 - Wiley Online Library
Objective Various commonly consumed foods have long been suspected of affecting the
serum uric acid level, but few data are available to support or refute this impression. Our …

Hyperuricemia and coronary heart disease: a systematic review and meta‐analysis

SY Kim, JP Guevara, KM Kim, HK Choi… - Arthritis Care & …, 2010 - Wiley Online Library
Objective The role of serum uric acid as an independent risk factor for cardiovascular disease
remains unclear, although hyperuricemia is associated with cardiovascular disease such …