User profiles for Hugues Allard-Chamard
Hugues Allard-ChamardUniversity de Sherbrooke Verified email at USherbrooke.ca Cited by 1393 |
[PDF][PDF] Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19
…, HH Kuo, J Boucau, JR Farmer, H Allard-Chamard… - Cell, 2020 - cell.com
Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability,
as seen with other human coronavirus epidemics. To address the underlying etiology, we …
as seen with other human coronavirus epidemics. To address the underlying etiology, we …
Identification of galectin-3 as an autoantigen in patients with IgG4-related disease
… AlSalem MBBS, MMSc b c ∗ , Hamid Mattoo PhD b , Emanuel Della-Torre MD, PhD b d ,
Vinay Mahajan MBBS, PhD b e , Gayathri Ganesh BS b , Hugues Allard-Chamard MD, PhD b , …
Vinay Mahajan MBBS, PhD b e , Gayathri Ganesh BS b , Hugues Allard-Chamard MD, PhD b , …
[HTML][HTML] Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis
Systemic sclerosis (SSc) is an autoimmune fibrotic disease whose pathogenesis is poorly
understood and lacks effective therapies. We undertook quantitative analyses of T cell …
understood and lacks effective therapies. We undertook quantitative analyses of T cell …
CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease
Background IgG 4 -related disease (IgG 4 -RD) is an immune-mediated fibrotic disorder that
has been linked to CD4 + cytotoxic T lymphocytes (CD4 + CTLs). The effector phenotype of …
has been linked to CD4 + cytotoxic T lymphocytes (CD4 + CTLs). The effector phenotype of …
Interleukin-15 in autoimmunity
H Allard-Chamard, HK Mishra, M Nandi, M Mayhue… - Cytokine, 2020 - Elsevier
Interleukin-15 (IL-15) is a member of the IL-2 family of cytokines, which use receptor complexes
containing the common gamma (γ c ) chain for signaling. IL-15 plays important roles in …
containing the common gamma (γ c ) chain for signaling. IL-15 plays important roles in …
ADE and hyperinflammation in SARS-CoV2 infection-comparison with dengue hemorrhagic fever and feline infectious peritonitis
M Cloutier, M Nandi, AU Ihsan, HA Chamard… - Cytokine, 2020 - Elsevier
The COVID-19 pandemic has rapidly spread around the world with significant morbidity and
mortality in a subset of patients including the elderly. The poorer outcomes are associated …
mortality in a subset of patients including the elderly. The poorer outcomes are associated …
Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single …
…, B Burington, H Liu, H Allard-Chamard… - The Lancet …, 2023 - thelancet.com
Background Obexelimab is a bifunctional, non-cytolytic, humanised monoclonal antibody
that binds CD19 and Fc gamma receptor IIb to inhibit B cells, plasmablasts, and CD19-…
that binds CD19 and Fc gamma receptor IIb to inhibit B cells, plasmablasts, and CD19-…
CD4+ CTLs in fibrosing mediastinitis linked to Histoplasma capsulatum
H Allard-Chamard, F Alsufyani, N Kaneko… - The Journal of …, 2021 - journals.aai.org
Although fibrotic disorders are frequently assumed to be linked to T H2 cells, quantitative tissue
interrogation studies have rarely been performed to establish this link and certainly many …
interrogation studies have rarely been performed to establish this link and certainly many …
[HTML][HTML] B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers
The B1 and B2 lineages of B cells contribute to protection from pathogens in distinct ways.
The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here …
The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here …
[PDF][PDF] Extrafollicular IgD− CD27− CXCR5− CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19
Although therapeutic B cell depletion dramatically resolves inflammation in many diseases
in which antibodies appear not to play a central role, distinct extrafollicular pathogenic B cell …
in which antibodies appear not to play a central role, distinct extrafollicular pathogenic B cell …