ABSTRACT Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell
checkpoint and plays a central role in regulating T cell exhaustion. Binding of PD-1 to its …

Background Data regarding clinical outcomes after optical coherence tomography (OCT)–guided
percutaneous coronary intervention (PCI) as compared with angiography-guided PCI …

Background Acute lung injury (ALI) is characterized by suppressed fibrinolytic activity in
bronchoalveolar lavage fluid (BALF) attributed to elevated plasminogen activator inhibitor-1 (PAI-…

Regulatory T (T reg ) cells suppress autoimmune disease, and impaired T reg cell function
is associated with rheumatoid arthritis. Here we demonstrate that forkhead box P3 (FOXP3) …

Itch-specific neurons have been sought for decades. The existence of such neurons has been
doubted recently as a result of the observation that itch-mediating neurons also respond to …

BACKGROUND: Addictions are defined by a loss of flexible control over behavior. The
development of response habits might reflect early changes in behavioral control. The following …

T cell activation and function are critically regulated by positive and negative costimulatory
molecules. Aberrant expression and function of costimulatory molecules have been …

Osteopontin (OPN) is an extracellular matrix protein of pleiotropic properties and has been
recently recognized as a potential inflammatory cytokine. In this study, we demonstrate, for …

Background PRMT5 is a type II protein arginine methyltransferase that methylates histone
or non-histone proteins. Arginine methylation by PRMT5 has been implicated in gene …

The effects of ammonia concentration on the performance and stability of mono-fermentation
of chicken manure were investigated in a lab-scale continuous stirred tank reactor at 40 C. …