Objective. We have recently discovered that women with primary and secondary Sjögren's
syndrome are androgen‐deficient. We hypothesize that this hormone insufficiency contributes …

OBJECTIVE: We hypothesize that androgen deficiency is a critical etiologic factor in the
pathogenesis of aqueous-deficient and evaporative dry eye in Sjögren's syndrome (SS). We …

Background. The expression of Fas ligand (FasL) in the eye has been proposed to be an
important component of ocular immune privilege. Since the unusually favorable outcome of …

methods. Normal human donor corneal epithelium was examined by fluorescence microscopy
with single and double staining for multiple markers. Morphologic studies were also …

purpose. To determine the effects of proinflammatory cytokines on differential gene expression
profiles in the human corneal endothelium (HCE), by using a cDNA expression array. …

Purpose: To study the relation between posterior vitreous detachment (PVD) and progression
of diabetic retinopathy (DR), based on our observation that proliferative DR is rare in …

Background We previously reported a new diabetic strain of the Sprague‐Dawley rat, named
the Spontaneously Diabetic Torii (SDT) rat. The purpose of the present study was to report …

Significant, sex-associated differences exist in the physiology and pathophysiology of the
lacrimal gland. We hypothesize that many of these differences are due to fundamental …

The objective of this study was to determine the nature and extent of androgen influence on
gene expression in the lacrimal gland. Lacrimal glands were obtained from orchiectomized …

Background. Cytokine profile is a key in understanding the mechanisms of allograft rejection.
Cytokine expression in the aqueous humor and the correlation between the aqueous …