A more efficient method to generate integration-free human iPS cells

…, T Kunisada, M Takahashi, J Takahashi, H Saji… - Nature …, 2011 - nature.com
We report a simple method, using p53 suppression and nontransforming L-Myc, to generate
human induced pluripotent stem cells (iPSCs) with episomal plasmid vectors. We generated …

High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism

…, K Matsuo, K Kashiwase, H Inoko, H Saji… - Blood, The Journal …, 2007 - ashpublications.org
In allogenic hematopoietic stem-cell transplantation, an effect of HLA locus mismatch in
allele level on clinical outcome has been clarified. However, the effect of each HLA allele …

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product

…, EH Kim, T Soma, M Asada, K Ueda, E Maruya, H Saji… - Immunogenetics, 2000 - Springer
The product of the Wilms' tumor gene WT1 is a transcription factor overexpressed not only in
leukemic blast cells of almost all patients with acute myeloid leukemia, acute lymphoid …

Feasibility of HLA-haploidentical hematopoietic stem cell transplantation between noninherited maternal antigen (NIMA)–mismatched family members linked with long …

…, K Oka, H Kimura, M Itoh, T Inukai, E Maruya, H Saji… - Blood, 2004 - ashpublications.org
Based on the hypothesis that long-term fetomaternal microchimerism is associated with
acquired immunologic hyporesponsiveness to noninherited maternal antigens (NIMAs) or …

Epitopes of human leukocyte antigen class I antibodies found in sera of normal healthy males and cord blood

…, A Nguyen, N Sasaki, LE Morales-Buenrostro, H Saji… - Human immunology, 2009 - Elsevier
This study defines 96 epitopes targeted by human leukocyte antigen (HLA) antibodies reported
in the sera of normal healthy males with no history of deliberate alloimmunizations and in …

HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism

…, K Matsuo, K Kashiwase, H Inoko, H Saji… - Blood, The Journal …, 2009 - ashpublications.org
The finding that the risk of relapse in hematologic malignancy decreases after allogeneic
hematopoietic stem cell transplantation (HSCT) has lead to the concept of a graft-versus-…

[HTML][HTML] Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell …

…, K Matsuo, K Kashiwase, H Inoko, H Saji… - Biology of Blood and …, 2007 - Elsevier
The responsible human leukocyte antigen (HLA) locus and the role of killer immunoglobulin-like
receptor (KIR) ligand matching on transplantation outcome were simultaneously …

A clinical, pathological, and genetic characterization of methotrexate-associated lymphoproliferative disorders

…, K Yurugi, Y Miura, T Maekawa, H Saji… - The Journal of …, 2014 - jrheum.org
Objective. Methotrexate-associated lymphoproliferative disorders (MTX-LPD) often regress
spontaneously during MTX withdrawal, but the prognostic factors remain unclear. The aim of …

Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation

…, N Nishio, A Hama, H Yagasaki, H Saji… - Blood, The Journal …, 2010 - ashpublications.org
We investigated human leukocyte antigen (HLA) expression on leukemic cells derived from
patients at diagnosis and relapse after hematopoietic stem cell transplantation (HSCT) using …

Fetal–maternal microchimerism: impact on hematopoietic stem cell transplantation

…, T Teshima, K Matsuoka, E Maruya, H Saji - Current opinion in …, 2005 - Elsevier
Reciprocal cell traffic between mother and fetus during pregnancy gives rise to postpartum
fetal–maternal lymphohematopoietic microchimerism, which is frequently detected in blood or …