The current guideline represents the 6th edition of the “Japanese Clinical Practice Guideline
for Diabetes” which has been revised every three years since its first appearance in 2004 to …

Since its inception in 2004, the “Clinical Practice Guidelines for the Treatment of Diabetes”
has attempted to promote evidence-based, rational, efficient and standardized clinical …

Background Epidemiological and clinical evidence suggests that an increased intake of long-chain
n-3 fatty acids protects against mortality from coronary artery disease. We aimed to …

Object A modified World Federation of Neurosurgical Societies scale (m-WFNS scale) for
aneurysmal subarachnoid hemorrhage (SAH) recently has been proposed, in which patients …

BACKGROUND: The mortality and morbidity rates of various cardiovascular diseases differ
between Western countries and Japan. The age- and gender-specific prevalence rate of …

Aims The therapeutic strategy for heart failure with preserved ejection fraction (HFPEF) has
not been established. The Japanese Diastolic Heart Failure Study (J‐DHF) is a multicentre, …

BACKGROUND: Japan EPA Lipid Intervention Study (JELIS) was a large-scale clinical trial
examining the effects of eicosapentaenoic acid (EPA) on coronary artery disease (CAD) in …

Background and Purpose— The JELIS trial examined the preventive effect of eicosapentaenoic
acid (EPA) against coronary artery diseases. Hypercholesterolemic patients received …

Objective A multicentre cohort follow-up study of a large number of patients with gastric
mucosa-associated lymphoid tissue (MALT) lymphoma was conducted to elucidate the long-term …

Background and Purpose— Although the efficacy of anticoagulant therapy for primary
prevention of stroke in patients with nonvalvular atrial fibrillation (NVAF) has been established, …