C-reactive protein (CRP) is well-known as a sensitive albeit unspecific biomarker of inflammation.
In most rheumatic conditions, the level of this evolutionarily highly conserved pattern …

Objective C‐reactive protein (CRP) is synthesized by hepatocytes in response to interleukin‐6
(IL‐6) during inflammation. Despite raised IL‐6 levels and extensive systemic …

Background: Efficient healthcare based on prognostic variables in hospitalised patients with
COVID-19 could reduce the risk of complications and death. Recently, soluble urokinase …

Systemic lupus erythematosus (SLE) is a potentially severe autoimmune condition with an
unpredictable disease course, often with fluctuations in disease activity over time. Long term …

Objective. Analysis of antibodies against dsDNA is an important diagnostic tool for systemic
lupus erythematosus (SLE), and changes in anti-dsDNA antibody levels are also used to …

Objectives Patients with systemic lupus erythematosus (SLE) often display modest elevations
of C-reactive protein (CRP) despite raised disease activity and increased interleukin (IL-) 6…

Objectives Type I interferons (IFNs) are central and reflective of disease activity in systemic
lupus erythematosus (SLE). However, IFN-α levels are notoriously difficult to measure and …

Assessments of disease activity and organ damage in systemic lupus erythematosus (SLE)
remain challenging because of the lack of reliable biomarkers and disease heterogeneity. …

Presence of autoantibodies targeting nuclear constituents, ie, double-stranded DNA and
small nuclear ribonucleoproteins (snRNPs), remain a cornerstone in systemic lupus …

Objective Copy number variation of the C4 complement components, C4A and C4B, has been
associated with systemic inflammatory autoimmune diseases. This study was undertaken …