The German etanercept registry for treatment of juvenile idiopathic arthritis

G Horneff, H Schmeling, T Biedermann… - Annals of the …, 2004 - ard.bmj.com
Objective: To describe a registry set up to monitor children treated with etanercept in Germany
and Austria. Methods: Giannini’s criteria, duration of morning stiffness, number of swollen, …

Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial

…, V Chasnyk, M Lerman, K Nanda, H Schmeling… - The Lancet, 2021 - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor. This trial assessed the efficacy and
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort

…, L Spiegel, SE Turvey, H Schmeling… - Annals of the …, 2015 - ard.bmj.com
Objective To describe clinical outcomes of juvenile idiopathic arthritis (JIA) in a prospective
inception cohort of children managed with contemporary treatments. Methods Children newly …

Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations

…, N Wulffraat, H Schmeling… - … : Official Journal of …, 2004 - Wiley Online Library
Objective Phagocytes are extensively involved in the synovial inflammation associated with
chronic arthritis. The aim of our study was to determine neutrophil activation in juvenile …

[HTML][HTML] Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

…, NM Ruth, M Rygg, H Schmeling… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Undifferentiated systemic autoinflammatory diseases (USAIDs) present
diagnostic and therapeutic challenges. Chronic interferon (IFN) signaling and cytokine …

Anti-HMGCR antibodies as a biomarker for immune-mediated necrotizing myopathies: A history of statins and experience from a large international multi-center study

…, A Doria, MY Choi, MJ Fritzler, H Schmeling… - Autoimmunity …, 2016 - Elsevier
In an effort to find naturally occurring substances that reduce cholesterol by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme
A reductase (HMGCR), statins were first discovered by Endo …

Consensus treatments for moderate juvenile dermatomyositis: beyond the first two months. Results of the second Childhood Arthritis and Rheumatology Research …

…, P Lawler, B Shaham, H Schmeling… - Arthritis care & …, 2012 - Wiley Online Library
Objective To use consensus methods and the considerable expertise contained within the
Childhood Arthritis and Rheumatology Research Alliance (CARRA) organization to extend …

Clinical characteristics of children with juvenile dermatomyositis: the Childhood Arthritis and Rheumatology Research Alliance Registry

…, ML Becker, EA Kessler, H Schmeling… - Arthritis care & …, 2014 - Wiley Online Library
Objective To investigate aspects of juvenile dermatomyositis (DM), including disease
characteristics and treatment, through a national multicenter registry. Methods Subjects meeting …

The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort

…, L Spiegel, SE Turvey, H Schmeling… - Annals of the …, 2016 - ard.bmj.com
Objective To describe probabilities and characteristics of disease flares in children with juvenile
idiopathic arthritis (JIA) and to identify clinical features associated with an increased risk …

Efficacy and safety of adalimumab as the first and second biologic agent in juvenile idiopathic arthritis: the German Biologics JIA Registry

H Schmeling, K Minden, I Foeldvari… - Arthritis & …, 2014 - Wiley Online Library
Schmeling has received honoraria for advisory board service from Roche, AbbVie, and Pfizer
… E-mail: heinrike.schmeling@albertahealthservices.ca. Submitted for publication November …