User profiles for Havva Keskin

Havva Keskin

Ankara Üniversitesi Tıp Fakültesi
Verified email at saglik.gov.tr
Cited by 296

Transcript-RNA-templated DNA recombination and repair

H Keskin, Y Shen, F Huang, M Patel, T Yang, K Ashley… - Nature, 2014 - nature.com
Homologous recombination is a molecular process that has multiple important roles in DNA
metabolism, both for DNA repair and genetic variation in all forms of life 1 . Generally, …

[HTML][HTML] Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

…, T Yang, P Xu, G Newnam, H Keskin… - Nature …, 2020 - nature.com
Despite the abundance of ribonucleoside monophosphates (rNMPs) in DNA, sites of rNMP
incorporation remain poorly characterized. Here, by using ribose-seq and Ribose-Map …

[PDF][PDF] Rad52 inverse strand exchange drives RNA-templated DNA double-strand break repair

OM Mazina, H Keskin, K Hanamshet, F Storici… - Molecular cell, 2017 - cell.com
RNA can serve as a template for DNA double-strand break repair in yeast cells, and Rad52,
a member of the homologous recombination pathway, emerged as an important player in …

[PDF][PDF] Genetic characterization of three distinct mechanisms supporting RNA-driven DNA repair and modification reveals major role of DNA polymerase ζ

C Meers, H Keskin, G Banyai, O Mazina, T Yang… - Molecular cell, 2020 - cell.com
DNA double-stranded breaks (DSBs) are dangerous lesions threatening genomic stability.
Fidelity of DSB repair is best achieved by recombination with a homologous template …

Transcript RNA supports precise repair of its own DNA gene

H Keskin, C Meers, F Storici - RNA biology, 2016 - Taylor & Francis
The transfer of genetic information from RNA to DNA is considered an extraordinary process
in molecular biology. Despite the fact that cells transcribe abundant amount of RNA with a …

DNA repair by RNA: Templated, or not templated, that is the question

C Meers, H Keskin, F Storici - DNA repair, 2016 - Elsevier
Cells are continuously exposed to both endogenous and exogenous sources of genomic
stress. To maintain chromosome stability, a variety of mechanisms have evolved to cope with …

The value of parathyroid scintigraphy on lesion detection in patients with normocalcemic primary hyperparathyroidism

S Gungor, F Dede, B Can, H Keskin, M Aras… - Revista Española de …, 2022 - Elsevier
Objective Primary hyperparathyroidism (PHPT) is one of the most frequent endocrine
diseases. Most of the patients with PHPT are asymptomatic, and only 20% of them become …

[PDF][PDF] Elevated neutrophil-lymphocyte ratio in patients with euthyroid chronic autoimmune thyreotidis

H Keskin, Y Kaya, K Cadirci, C Kucur, E Ziypak… - Endocrine …, 2016 - sciendo.com
Objective. The neutrophil-lymphocyte ratio (NLR), determined from peripheral blood, is
accepted as an available and practical indicator of the systemic inflammation. In this study, we …

Assessment of the new 2012 EULAR/ACR clinical classification criteria for polymyalgia rheumatica: a prospective multicenter study

…, B Kisacik, AM Onat, S Murat, H Keskin… - The Journal of …, 2016 - jrheum.org
Objective. To assess the performance of the new 2012 provisional European League Against
Rheumatism (EULAR)/American College of Rheumatology (ACR) polymyalgia rheumatica …

[HTML][HTML] Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death

L Kallay, H Keskin, A Ross, M Rupji, OA Moody… - Journal of neuro …, 2019 - Springer
Purpose Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous
comorbidities. MB is comprised of distinct molecular subgroups. Group 3 molecular …