There is increasing evidence that γδ T cells have potent innate antitumor activity. We
described previously that synthetic aminobisphosphonates are potent γδ T cell stimulatory …

Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

Objective Transient B cell depletion with the monoclonal anti‐CD20 antibody rituximab has
resulted in favorable clinical responses in patients with rheumatoid arthritis (RA). However, …

The CD19 antigen is a promising target for immunotherapy of acute lymphoblastic leukemia
(ALL), but CD19 − relapses remain a major challenge in about 10% to 20% of patients. Here…

Objective To prospectively analyse the risk for disease relapses in patients with rheumatoid
arthritis (RA) in sustained remission, either continuing, tapering or stopping disease-…

… Tony has received speaking fees (less than $10,000) from … Tony has received speaking fees
(less than $10,000) from … Tony has received speaking fees (less than $10,000) from Roche. …

Introduction Evidence from a number of open-label, uncontrolled studies has suggested that
rituximab may benefit patients with autoimmune diseases who are refractory to standard-of-…

Objective To evaluate the extent of intraarticular vascularization and pannus formation in
metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints of patients with …

Objectives: To assess the effect of sulfasalazine (SSZ) on inflammatory back pain (IBP) due
to active undifferentiated spondyloarthritis (uSpA) or ankylosing spondylitis in patients with …

Background Patients with inflammatory diseases, such as rheumatoid arthritis, often receive
glucocorticoids, but long-term use can produce adverse effects. Evidence from randomised …