Apoptosis in glomerular sclerosis

H Sugiyama, N Kashihara, H Makino, Y Yamasaki… - Kidney international, 1996 - Elsevier
Apoptosis in glomerular sclerosis. Glomerulosclerosis is characterized by progressive
extracellular matrix accumulation and glomerular cell loss. The role of glomerular cell apoptosis in …

Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney

…, M Kinomura, T Sugaya, H Sugiyama… - The FASEB …, 2005 - Wiley Online Library
Kidney is thought to be a regenerative organ in terms of repair from acute tubular injury. It is
unknown whether cell population contributes to repair disordered kidney. We attempted to …

[HTML][HTML] A decreased level of serum soluble Klotho is an independent biomarker associated with arterial stiffness in patients with chronic kidney disease

M Kitagawa, H Sugiyama, H Morinaga, T Inoue… - PloS one, 2013 - journals.plos.org
Background Klotho was originally identified in a mutant mouse strain unable to express the
gene that consequently showed shortened life spans. In humans, low serum Klotho levels …

Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy

…, H Kitayama, S Kitamura, Y Takazawa, H Sugiyama… - Diabetes, 2004 - Am Diabetes Assoc
In the early stage of diabetic nephropathy (one of the major microvascular complications of
diabetes) glomerular hyperfiltration and hypertrophy are observed. It is clinically important to …

[HTML][HTML] Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan

H Sugiyama, H Yokoyama, H Sato, T Saito… - Clinical and …, 2011 - Springer
Background The Committee for the Standardization of Renal Pathological Diagnosis and the
Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started …

Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus.

…, Y Yamasaki, M Maruyama, H Sugiyama… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: The metabolic syndrome, closely associated with cardiovascular disease, is
characterized by increased insulin resistance (IR). Although accelerated atherosclerosis is …

[HTML][HTML] Japan renal biopsy registry and Japan kidney disease registry: committee report for 2009 and 2010

H Sugiyama, H Yokoyama, H Sato, T Saito… - Clinical and …, 2013 - Springer
The Japan Renal Biopsy Registry (J-RBR) was started in 2007 and the Japan Kidney Disease
Registry (J-KDR) was then started in 2009 by the Committee for Standardization of Renal …

Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR)

H Yokoyama, H Sugiyama, H Sato, T Taguchi… - Clinical and …, 2012 - Springer
Background and objectives Data regarding renal disease in the elderly (age ≥65 years old)
and very elderly (age ≥80 years old) Japanese are extremely limited. The aim of this study …

[HTML][HTML] Prevalence of anemia in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney …

…, K Yamagata, I Narita, M Yanagita, H Sugiyama… - PloS one, 2020 - journals.plos.org
Background The Japan Chronic Kidney Disease Database (J-CKD-DB) is a nationwide
clinical database of patients with chronic kidney disease (CKD) based on electronic health …

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model

…, H Kitayama, Y Takazawa, K Hirokoshi, H Sugiyama… - Diabetes, 2005 - Am Diabetes Assoc
Diabetic nephropathy is one of the major microvascular complications in diabetes and is the
leading cause of end-stage renal disease worldwide. Among various factors, angiogenesis-…