The classification of glomerulonephritis in systemic lupus erythematosus revisited.The currently
used classification reflects our understanding of the pathogenesis of the various forms of …

There is a rapid global rise in obesity, and the link between obesity and diabetes remains
somewhat obscure. We identified an adipocytokine, designated as visceral adipose tissue-…

Background Plasma uric acid has been associated with hypertension in a variety of disorders,
and has been shown to be predictive of hypertension. The mechanistic role of uric acid in …

The most problematic issue in clinical nephrology is the relentless and progressive increase
in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic …

Objective To develop and validate revised classification criteria for granulomatosis with
polyangiitis (GPA). Methods Patients with vasculitis or comparator diseases were recruited into …

Objective To develop and validate revised classification criteria for eosinophilic granulomatosis
with polyangiitis (EGPA). Methods Patients with vasculitis or comparator diseases were …

Objective To develop and validate classification criteria for microscopic polyangiitis (MPA).
Methods Patients with vasculitis or comparator diseases were recruited into an international …

Background We previously estimated the prevalence of chronic kidney disease (CKD) stages
3–5 at 19.1 million based on data from the Japanese annual health check program for …

Background Accurate estimation of the glomerular filtration rate (GFR) is crucial for the
detection of chronic kidney disease (CKD). In clinical practice, GFR is estimated from serum …

Objective CD14+,CD16+ monocytes, identified as a minor population of monocytes in
human peripheral blood (PB), have been implicated in several inflammatory diseases. We …