Ongoing inflammation including activation of the complement system is a hallmark of
systemic lupus erythematosus (SLE). Antimicrobial neutrophil extracellular traps (NETs) are …

Objectives. Patients with SLE have an increased morbidity and mortality from cardiovascular
disease (CVD). The reason for this is not entirely understood, but is believed to be partly …

Anti-phospholipid (aPL) antibodies are important contributors to development of thrombosis
in patients with the autoimmune rheumatic disease systemic lupus erythematosus (SLE). …

Objective Levels of S100A8/A9, a proinflammatory and prothrombotic protein complex, are
increased in several diseases, and high levels predispose to cardiovascular disease (CVD). …

Objectives Endothelial dysfunction may be connected to cardiovascular disease (CVD) in
systemic lupus erythematosus (SLE). Type I interferons (IFNs) are central in SLE pathogenesis …

Serotonin, a highly pro-inflammatory molecule released by activated platelets, is formed by
tryptophan. Tryptophan is also needed in the production of kynurenine, a process mediated …

Objectives Systemic lupus erythematosus (SLE) is associated with elevated levels of S100A8/A9,
pro-inflammatory proteins mainly secreted by activated polymorphonuclear neutrophils …

Introduction Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or
episodic inflammation in many different organ systems, activation of leukocytes and …

Objectives. SLE is an autoimmune disease with increased cardiovascular morbidity and
platelet activation. In the general population, increased platelet size predicts platelet reactivity …

Objectives A single nucleotide polymorphism in the NCF1 gene (NCF1-339, rs201802880),
encoding NADPH oxidase type II subunit NCF1/p47 phox , reducing production of reactive …