… Additionally, a novel anti-claudin-3 antibody recognized cerebral capillary endothelial cell
tight junctions (Engelhardt and Wolburg, unpublished). The occurrence of claudin-1 in the …

The blood–brain barrier is essential for the maintainance and regulation of the neural
microenvironment. The blood–brain barrier endothelial cells comprise an extremely low rate of …

The microenvironment of the CNS is important for neuronal function, and the blood-brain
barrier is involved in its maintenance. The barrier is present in a complex cellular system at the …

… All specimens were osmicated in 1% cacodylate-buffered (0,1 M) OsO, for 1 h and then
dehydrated step by step in ethanol. In 7O% ethanol, they were blocstained with saturated uranyl …

The association of pericytes (PCs) to newly formed blood vessels has been suggested to
regulate endothelial cell (EC) proliferation, survival, migration, differentiation, and vascular …

… To functionally test barrier properties, we injected Evans blue ip 18 h before tissue harvesting.
At P14, extravasated Evans blue was apparent around many vessels after endothelial β-…

We have generated a novel transgenic mouse model on a C57BL/6J genetic background
that coexpresses KM670/671NL mutated amyloid precursor protein and L166P mutated …

… 5H), we observed enlarged mitochondria with disorganized cristae that were more
pronounced in cells overexpressing S399 mutant Omi/HtrA2 (Fig. 5I and J). Some of these …

… on tissue culture plates that were either coated for 16 h at 4C with laminin (cocultures with
choroid plexus epithelial cells) or for 16 h at 37C with collagen (cocultures with EpH4 cells). …

In the central nervous system (CNS) complex endothelial tight junctions (TJs) form a restrictive
paracellular diffusion barrier, the blood-brain barrier (BBB). During inflammation, BBB …