Pathways of apoptotic and non-apoptotic death in tumour cells
H Okada, TW Mak - Nature Reviews Cancer, 2004 - nature.com
Defects in cell-death pathways are hallmarks of cancer. Although resistance to apoptosis is
closely linked to tumorigenesis, tumour cells can still be induced to die by non-apoptotic …
closely linked to tumorigenesis, tumour cells can still be induced to die by non-apoptotic …
The 'hygiene hypothesis' for autoimmune and allergic diseases: an update
H Okada, C Kuhn, H Feillet… - Clinical & Experimental …, 2010 - academic.oup.com
According to the ‘hygiene hypothesis’, the decreasing incidence of infections in western
countries and more recently in developing countries is at the origin of the increasing incidence …
countries and more recently in developing countries is at the origin of the increasing incidence …
Immunotherapy response assessment in neuro-oncology: a report of the RANO working group
Immunotherapy is a promising area of therapy in patients with neuro-oncological malignancies.
However, early-phase studies show unique challenges associated with the assessment …
However, early-phase studies show unique challenges associated with the assessment …
[HTML][HTML] Evidence that fibroblasts derive from epithelium during tissue fibrosis
…, D Plieth, TM Danoff, C Xue, H Okada… - The Journal of …, 2002 - Am Soc Clin Investig
Interstitial fibroblasts are principal effector cells of organ fibrosis in kidneys, lungs, and liver.
While some view fibroblasts in adult tissues as nothing more than primitive mesenchymal …
While some view fibroblasts in adult tissues as nothing more than primitive mesenchymal …
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
We conducted a first-in-human study of intravenous delivery of a single dose of autologous
T cells redirected to the epidermal growth factor receptor variant III (EGFRvIII) mutation by a …
T cells redirected to the epidermal growth factor receptor variant III (EGFRvIII) mutation by a …
A global genetic interaction network maps a wiring diagram of cellular function
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
Non-Abelian discrete symmetries in particle physics
…, H Ohki, Y Shimizu, H Okada… - Progress of …, 2010 - academic.oup.com
We review pedagogically non-Abelian discrete groups, which play an important role in
particle physics. We show group-theoretical aspects for many concrete groups, such as …
particle physics. We show group-theoretical aspects for many concrete groups, such as …
Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet
…, T Fotsis, E Hämäläinen, T Hasegawa, H Okada - The American journal of …, 1991 - Elsevier
Epidemiologic studies revealed low mortality in hormone-dependent cancer in Japanese
women and men consuming a traditional diet. We previously found that certain diphenolic food …
women and men consuming a traditional diet. We previously found that certain diphenolic food …
Identification of membrane-type receptor for bile acids (M-BAR)
…, H Okada, E Sugiyama, T Nakamura, H Itadani… - Biochemical and …, 2002 - Elsevier
… cells/well) and incubated for 24 h at 37 C, washed twice with Opti-MEM (Life Technologies)
containing 1 mM 3-isobutyl-1-methylxanthine (IBMX) and incubated in fresh Opti-MEM …
containing 1 mM 3-isobutyl-1-methylxanthine (IBMX) and incubated in fresh Opti-MEM …
Identification and characterization of a fibroblast marker: FSP1.
F Strutz, H Okada, CW Lo, T Danoff… - The Journal of cell …, 1995 - rupress.org
… A genomic clone (7cG), encoding FSP1, was isolated from an NIH/3T3 genomic library in h
… Medium was changed 24 h later and cells were harvested 48 h after transfection by lysis in …
… Medium was changed 24 h later and cells were harvested 48 h after transfection by lysis in …