Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …

Japan shows the advantages and limitations of pursuing universal health coverage by
establishment of employee-based and community-based social health insurance. On the positive …

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock
2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and …

FOLLOWING the discovery of superconductivity at ∼30 K in La 2−x Ba x CuO 4 (ref. 1), a
large number of related compounds have been found that are superconducting at relatively …

Recent climatic changes have enhanced plant growth in northern mid-latitudes and high
latitudes. However, a comprehensive analysis of the impact of global climatic changes on …

Abstract Until recently, continuous monitoring of global vegetation productivity has not been
possible because of technological limitations. This article introduces a new satellite-driven …

Heart disease remains a major cause of death despite advances in medical technology.
Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a potentially promising …

… For the Western blotting analyses, cells were serum-deprived for 10 h in media and
treated with 10 nm MCP-1 for 5 min to detect the extracellular signal-regulated kinase (ERK) …

Background—An elevated plasma concentration of high-sensitivity C-reactive protein (hs-CRP)
is a strong predictor of cardiovascular events. However, there have been no longitudinal …

… Immunostaining revealed that the TiPSCs expressed the Nanog, Oct3/4, SSEA3, SSEA4,
Tra-1-60, and Tra-1-81 proteins (Figure 1H). High telomerase activity is also an important …