[HTML][HTML] Incidence of hepatitis B virus reactivation in patients with resolved infection on immunosuppressive therapy for rheumatic disease: a multicentre, prospective …

…, Y Koyama, K Arii, T Kitaori, H Hagiyama… - Annals of the …, 2017 - ard.bmj.com
Background Although the reactivation of hepatitis B virus (HBV) is recognised as a serious
complication in patients with rheumatic disease (RD) receiving immunosuppressive drugs (…

[HTML][HTML] Optimal regimens of sulfamethoxazole-trimethoprim for chemoprophylaxis of Pneumocystis pneumonia in patients with systemic rheumatic diseases: results …

…, M Soejima, T Sugihara, H Hagiyama… - Arthritis Research & …, 2017 - Springer
Background Sulfamethoxazole-trimethoprim (SMX/TMP) is a standard drug for the
prophylaxis of Pneumocystis pneumonia (PJP) in immunosuppressed patients with systemic …

Efficient detection of somatic UBA1 variants and clinical scoring system predicting patients with variants in VEXAS syndrome

…, R Motohashi, H Hagiyama, M Itagane, H Teruya… - …, 2023 - academic.oup.com
Objectives To efficiently detect somatic UBA1 variants and establish a clinical scoring
system predicting patients with pathogenic variants in VEXAS (vacuoles, E1 enzyme, X-linked, …

Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein–dependent and–independent pathways by cyclin‐dependent kinase 4/6

Y Nonomura, K Nagasaka, H Hagiyama… - … : Official Journal of …, 2006 - Wiley Online Library
… ) plus tumor necrosis factor α (TNFα), and 3 H-thymidine incorporation was assessed 3 days
later (left). Mean reduction in 3 H-thymidine incorporation induced by p16 INK4a was 83% …

[HTML][HTML] Risk stratification and clinical course of hepatitis B virus reactivation in rheumatoid arthritis patients with resolved infection: final report of a multicenter …

…, Y Koyama, K Arii, T Kitaori, H Hagiyama… - Arthritis research & …, 2019 - Springer
Background The prophylaxis for hepatitis B virus (HBV) reactivation assumes that hepatic
injury after reactivation is often rapidly progressive and can evoke fulminant hepatitis. The …

Sudden cardiac death associated with Churg-Strauss syndrome

…, M Kurabayashi, K Azegami, H Hagiyama… - Circulation …, 2009 - jstage.jst.go.jp
… At 02.00 h on the 5th hospital day, he had an episode of grand-mal chest pain with ECG
findings of a down-slopetype ST-depression in leads I, aVL, and V4–6. The chest pain persisted …

Vertebral fracture and bone mineral density in women receiving high dose glucocorticoids for treatment of autoimmune diseases.

…, J Kaburaki, H Kameda, A Suwa, H Hagiyama… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: To evaluate the factors influencing the occurrence of vertebral fracture in
patients receiving high dose glucocorticoids (GC). METHODS: A cross-sectional study was …

Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse …

…, M Harigai, F Mizoguchi, H Iwai, H Hagiyama… - Modern …, 2006 - Taylor & Francis
We describe two cases of leflunomide-related interstitial pneumonia (IP). A 75-year-old woman
with rheumatoid arthritis (RA) developed rapidly progressing IP 45 days after institution of …

Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1 or CrmA-sensitive caspases but is …

T Yoshida, T Higuchi, H Hagiyama… - International …, 2000 - academic.oup.com
… within 48 h, whereas only a small fraction of mature B cells undergo apoptosis in 48 h by
milder … (21) have demonstrated that treatment with soluble anti-Ig antibody for 24 h induces …

An open-label, randomized controlled trial of sulfamethoxazole–trimethoprim for Pneumocystis prophylaxis: results of 52-week follow-up

…, M Soejima, T Sugihara, H Hagiyama… - … Advances in Practice, 2020 - academic.oup.com
Objectives The aim was to investigate the long-term prophylactic efficacy, drug retention
and safety of low-dose sulfamethoxazole–trimethoprim (SMX/TMP) prophylaxis against …