Interindividual gene copy-number variation (CNV) of complement component C4 and its
associated polymorphisms in gene size (long and short) and protein isotypes (C4A and C4B) …

Objective To examine the safety and efficacy of the interleukin‐1 (IL‐1) receptor antagonist
anakinra as first‐line therapy for systemic juvenile idiopathic arthritis (JIA). Methods Patients …

Objective To determine whether aggressive treatment initiated early in the course of rheumatoid
factor (RF)–positive or RF‐negative polyarticular juvenile idiopathic arthritis (JIA) can …

Objective Juvenile localized scleroderma (LS) is a chronic inflammatory skin disorder
associated with substantial morbidity and disability. Although a wide range of therapeutic …

Objective To compare the criteria for Wegener's granulomatosis (WG) of the American
College of Rheumatology (ACR) with those of the European League Against Rheumatism/…

Objective. To develop and evaluate a Localized Scleroderma (LS) Skin Severity Index (LoSSI)
and global assessments’ clinimetric property and effect on quality of life (QOL). Methods. …

Objective To uniquely classify children with microscopic polyangiitis (MPA), to describe their
demographic characteristics, presenting clinical features, and initial treatments in …

Background: Lack of adherence is a ubiquitous problem which can be a hindrance in the
treatment of chronic conditions like systemic lupus erythematosus (SLE). Objectives: A random …

Objective To evaluate risk factors for subclinical atherosclerosis in a population of patients
with pediatric systemic lupus erythematosus (SLE). Methods In a prospective multicenter study…

OBJECTIVE: To describe the health and functional status of children with juvenile rheumatoid
arthritis (JRA) diagnosed in the early 1990s. METHODS: Patients were obtained from the …