Objective: The Western Ontario and McMaster Universities (WOMAC) Osteoarthritis (OA) Index
is a tested questionnaire to assess symptoms and physical functional disability in patients …

Osteoarthritis (OA) is a complex disease whose pathogenesis includes the contribution of
biomechanical and metabolic factors which, altering the tissue homeostasis of articular …

Scleroderma renal crisis (SRC) occurs in 5–10% of SSc patients, who may present with an
abrupt onset of hypertension, acute renal failure, headaches, fevers, malaise, hypertensive …

OBJECTIVE: To evaluate the risk of serious infections (SIs) in RA patients receiving anti-TNF
therapy on the basis of the data included in the GISEA register. METHODS: The study …

Objective. We aimed to investigate the expression of nerve growth factor (NGF) and high
affinity NGF receptor (p140 TrkA) on chondrocytes from human healthy and osteoarthritic …

OBJECTIVE: To assess the prevalence of good clinical response and remission in rheumatoid
arthritis (RA) patients with longstanding disease treated with anti-tumor necrosis factor-…

Objective. Rheumatoid arthritis (RA) and psoriatic arthritis (PA) are both ch ronic rheumatic
inflammatory diseases characterized by disruption of the extra-cellular matrix (ECM) protein …

Obesity is one of the main risk factors for osteoarthritis (OA). For many years the association
of obesity and OA has been simply attributed to the effects of overload on weight-bearing …

Abnormalities of central pain processing play an important role in the pathophysiology of
fibromyalgia (FM). The aims of the present study were to: 1) evaluate habituation of laser-…

A complex web of dynamic relationships between innate and adaptive immunity is now
evident for many autoinflammatory and autoimmune disorders, the first deriving from abnormal …