User profiles for GERALDO ALEIXO PASSOS
 | geraldo a passos*University of São Paulo Verified email at usp.br Cited by 3202 |
Post-transcriptional markers associated with clinical complications in Type 1 and Type 2 diabetes mellitus
…, CD Polli, MC e Silva, CC Alves, GA Passos… - Molecular and cellular …, 2019 - Elsevier
The delayed diagnosis and the inadequate treatment of diabetes increase the risk of chronic
complications. The study of regulatory molecules such as miRNAs can provide expression …
complications. The study of regulatory molecules such as miRNAs can provide expression …
The Autoimmune Regulator (Aire) transactivates HLA‐G gene expression in thymic epithelial cells
BL Melo‐Lima, I Poras, GA Passos, ED Carosella… - …, 2019 - Wiley Online Library
The Autoimmune Regulator (Aire) protein coordinates the negative selection of developing
thymocytes by inducing the expression of hundreds of tissue‐specific antigens within the …
thymocytes by inducing the expression of hundreds of tissue‐specific antigens within the …
[HTML][HTML] The thymic orchestration involving Aire, miRNAs, and cell–cell interactions during the induction of central tolerance
GA Passos, DA Mendes-da-Cruz… - Frontiers in …, 2015 - frontiersin.org
Developing thymocytes interact sequentially with two distinct structures within the thymus:
the cortex and medulla. Surviving single-positive and double-positive thymocytes from the …
the cortex and medulla. Surviving single-positive and double-positive thymocytes from the …
[HTML][HTML] Novel Dual AChE and ROCK2 Inhibitor Induces Neurogenesis via PTEN/AKT Pathway in Alzheimer's Disease Model
Alzheimer’s disease (AD) is a progressive and complex neurodegenerative disease.
Acetylcholinesterase inhibitors (AChEIs) are a major class of drugs used in AD therapy. ROCK2, …
Acetylcholinesterase inhibitors (AChEIs) are a major class of drugs used in AD therapy. ROCK2, …
Aire knockdown in medullary thymic epithelial cells affects Aire protein, deregulates cell adhesion genes and decreases thymocyte interaction
…, DS Lima, KF Bombonato-Prado, GA Passos - Molecular …, 2016 - Elsevier
We demonstrate that even a partial reduction of Aire mRNA levels by siRNA-induced Aire
knockdown (Aire KD) has important consequences to medullary thymic epithelial cells (mTECs)…
knockdown (Aire KD) has important consequences to medullary thymic epithelial cells (mTECs)…
[HTML][HTML] RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and …
…, DA Magalhães, M Dardenne, GA Passos… - BMC genomics, 2010 - Springer
Background The thymus is a central lymphoid organ, in which bone marrow-derived T cell
precursors undergo a complex process of maturation. Developing thymocytes interact with …
precursors undergo a complex process of maturation. Developing thymocytes interact with …
Effect of cell source and osteoblast differentiation on gene expression profiles of mesenchymal stem cells derived from bone marrow or adipose tissue
Mesenchymal stem cells (MSCs) have been used in therapies for bone tissue healing. The
aim of this study was to investigate the effect of cell source and osteoblast differentiation on …
aim of this study was to investigate the effect of cell source and osteoblast differentiation on …
Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX …
…, C Macedo, DM Rassi, GA Passos… - The Journal of …, 2012 - jrheum.org
Objective. We aimed to evaluate whether the differential gene expression profiles of
patients with rheumatoid arthritis (RA) could distinguish responders from nonresponders to …
patients with rheumatoid arthritis (RA) could distinguish responders from nonresponders to …
Time Course of c-fos, vasopressin and oxytocin mRNA Expression in the Hypothalamus Following Long-Term Dehydration
This study presents a time course analysis of the messenger RNA (mRNA) levels of c-fos,
vasopressin (VP), and oxytocin (OT) in the paraventricular (PVN) and supraoptic nucleus (SON…
vasopressin (VP), and oxytocin (OT) in the paraventricular (PVN) and supraoptic nucleus (SON…
[HTML][HTML] Identification of microRNAs with dysregulated expression in status epilepticus induced epileptogenesis
The involvement of miRNA in mesial temporal lobe epilepsy (MTLE) pathogenesis has
increasingly become a focus of epigenetic studies. Despite advances, the number of known …
increasingly become a focus of epigenetic studies. Despite advances, the number of known …