User profiles for G. HERBEIN
Georges HerbeinProfessor of Medicine University of Franche-Comté CHU Besançon Verified email at univ-fcomte.fr Cited by 10037 |
Tumor Necrosis Factor (TNF)–α and TNF Receptors in Viral Pathogenesis
G Herbein, WA O'brien - … of the Society for Experimental Biology …, 2000 - Wiley Online Library
… Recently a structural homology of the central conserved region of the attachment protein G
of … This homology suggests that the cysteine noose of RSV-G may interfere with the antiviral …
of … This homology suggests that the cysteine noose of RSV-G may interfere with the antiviral …
[HTML][HTML] HIV-1 latency in monocytes/macrophages
… APOBEC3 plays an important role in triggering G to A hypermutation of HIV-1 genome (Figure
1). Notably, SAMHD1 reduces the dNTPs pool in macrophages by hydrolyzing dNTPs into …
1). Notably, SAMHD1 reduces the dNTPs pool in macrophages by hydrolyzing dNTPs into …
[HTML][HTML] The eEF1A proteins: at the crossroads of oncogenesis, apoptosis, and viral infections
Eukaryotic translation elongation factors 1 alpha, eEF1A1 and eEF1A2, are not only translation
factors, but also pleiotropic proteins that are highly expressed in human tumors, including …
factors, but also pleiotropic proteins that are highly expressed in human tumors, including …
Interleukin‐13 alters the activation state of murine macrophages in vitro: Comparison with interleukin‐4 and interferon‐γ
AG Doyle, G Herbein, LJ Montaner… - European journal of …, 1994 - Wiley Online Library
Interleukin (IL)‐13 is a newly described cytokine expressed by activated lymphocytes. We
examined the effects of the murine recombinant cytokine on the phenotype and activation …
examined the effects of the murine recombinant cytokine on the phenotype and activation …
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
G Herbein, U Mahlknecht, F Batliwalla, P Gregersen… - Nature, 1998 - nature.com
… We therefore investigated the effect of pertussis toxin, an inhibitor of signal transduction by
chemokine receptors which are coupled to G proteins, and found that, as expected from our …
chemokine receptors which are coupled to G proteins, and found that, as expected from our …
[HTML][HTML] Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection
…, A Burny, C Rouzioux, S De Wit, G Herbein… - PloS one, 2009 - journals.plos.org
… U1 (panels A, B and C), J-Lat 15.4 (panels D, E and F) or J-Lat 8.4 (panels G, H and I) cells
… (inductions from 14- to 72-fold) to activate all the subtype LTRs, except the subtype G LTR. …
… (inductions from 14- to 72-fold) to activate all the subtype LTRs, except the subtype G LTR. …
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion
A Varin, S Mukhopadhyay, G Herbein… - Blood, The Journal of …, 2010 - ashpublications.org
Alternatively activated macrophages play an important role in host defense in the context of
a T helper type 2 (Th2) microenvironment such as parasitic infection. However, the role of …
a T helper type 2 (Th2) microenvironment such as parasitic infection. However, the role of …
[HTML][HTML] Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage
V Le Douce, G Herbein, O Rohr, C Schwartz - Retrovirology, 2010 - Springer
The introduction of the highly active antiretroviral therapy (HAART) has greatly improved
survival. However, these treatments fail to definitively cure the patients and unveil the presence …
survival. However, these treatments fail to definitively cure the patients and unveil the presence …
Mixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients
…, C Dirand, A Varin, W Chen, G Herbein - Clinical Infectious …, 2004 - academic.oup.com
On the basis of sequence variation in the UL55 gene that encodes glycoprotein B (gB),
human cytomegalovirus (CMV) can be classified into 4 gB genotypes. The goal of the present …
human cytomegalovirus (CMV) can be classified into 4 gB genotypes. The goal of the present …
[HTML][HTML] The macrophage in HIV-1 infection: from activation to deactivation?
G Herbein, A Varin - Retrovirology, 2010 - Springer
Macrophages play a crucial role in innate and adaptative immunity in response to
microorganisms and are an important cellular target during HIV-1 infection. Recently, the …
microorganisms and are an important cellular target during HIV-1 infection. Recently, the …