Β-1, 4-smallcap˜ D-Xylan-degrading enzyme systems: biochemistry, molecular biology and applications.

MP Coughlan, GP Hazlewood - Biotechnology and Applied …, 1993 - cabdirect.org
Heteropolysaccharides, based on a backbone structure of β-1, 4-linked smallcapD-xylose
residues, and collectively referred to as the β-1, 4-smallcapD-xylans, constitute the main …

Bacterial cellulases and xylanases

HJ Gilbert, GP Hazlewood - Microbiology, 1993 - microbiologyresearch.org
Although this review focusses primarily on bacterial cellulases and xylanases, there is
considerable overlap in the molecular biology and biochemistry of prokaryotic and fungal forms of …

Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti‐rheumatic drugs for rheumatoid arthritis: A …

GS Hazlewood, C Barnabe… - Cochrane Database …, 2016 - cochranelibrary.com
… This review is also published as an abridged version that presents the results for the major
outcomes (Hazlewood 2016). As each article underwent a separate peer‐review process, …

Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis

…, TA Furukawa, B Rochwerg, GS Hazlewood… - Journal of clinical …, 2018 - Elsevier
This article describes conceptual advances of the Grading of Recommendations Assessment,
Development, and Evaluation (GRADE) working group guidance to evaluate the certainty …

[HTML][HTML] Past and future burden of inflammatory bowel diseases based on modeling of population-based data

…, JA Avina-Zubieta, A Bitton, MW Carroll, G Hazlewood… - Gastroenterology, 2019 - Elsevier
Background & Aims Inflammatory bowel diseases (IBDs) exist worldwide, with high prevalence
in North America. IBD is complex and costly, and its increasing prevalence places a …

GRADE approach to drawing conclusions from a network meta-analysis using a partially contextualised framework

…, A Izcovich, B Rochwerg, ID Florez, G Hazlewood… - bmj, 2020 - bmj.com
This article describes GRADE (grading of recommendations assessment, development and
evaluation) guidance on how to make conclusions from a network meta-analysis of …

Comparative effectiveness of immunosuppressants and biologics for inducing and maintaining remission in Crohn's disease: a network meta-analysis

GS Hazlewood, A Rezaie, M Borman, R Panaccione… - Gastroenterology, 2015 - Elsevier
Background & Aims There is controversy regarding the best treatment for patients with
Crohn’s disease because of the lack of direct comparative trials. We compared therapies for …

Systematic review with meta‐analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis …

A Cholapranee, GS Hazlewood… - Alimentary …, 2017 - Wiley Online Library
Background Mucosal healing is an important therapeutic endpoint in the management of
Crohn's disease ( CD ) and ulcerative colitis ( UC ). Limited data exist regarding the …

Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity

…, A BORASTON, GP HAZLEWOOD… - Biochemical …, 1998 - portlandpress.com
… Insoluble material was sedimented by centrifugation at 30 000 g for 30 min at 4 mC. The CBD
… the CBD preparations by centrifugation at 30 000 g for 30min, followed by filtration through …

Canadian Rheumatology Association recommendations for pharmacological management of rheumatoid arthritis with traditional and biologic disease-modifying …

VP Bykerk, P Akhavan, GS Hazlewood… - The Journal of …, 2012 - jrheum.org
Objective. The Canadian Rheumatology Association (CRA) has developed recommendations
for the pharmacological management of rheumatoid arthritis (RA) with traditional and …