Evidence from animal models and prospective studies of RA, multiple sclerosis, and type-1
diabetes suggest an important role for vitamin D as a modifiable environmental factor in …

Due to the female predominance of autoimmune diseases, the role of gender and sex
hormones in the immune system is of long-term interest. Estrogen's primary effects are mediated …

Systemic lupus erythematosus is a prototypic autoimmune disease characterized by
autoantibody production and immune complex formation/deposition in target organs such as the …

… (0.5 g per square meter of body-surface area, increased to 1.0 g per square meter) as induction
therapy for active lupus nephritis. A change to the alternative regimen was allowed at 12 …

… Effect of TNF Antibody Injections on Body Weights As described in the text, TTP (/) mice from
seven litters (each litter is labeled A–G) were injected at weekly intervals starting on day 10 …

Objective Umbilical cord (UC)–derived mesenchymal stem cells (MSCs) have shown marked
therapeutic effects in a number of diseases in animal studies, based on their potential for …

We previously produced three congenic strains carrying lupus susceptibility genes (Sle1-Sle3)
from the lupus-prone NZM2410 mouse on the C57BL/6 background and characterized …

… Complete blood count at 1-month follow-up showed normal white cell count (4.7×10 9
cells/litre), haemoglobin 10.5 g/dl and an improved platelet count (95×10 9 cells/litre). …

… 15,000 g for 10 minutes at 4C, and the protein in the supernatants was precipitated with 1
ml of acetone overnight at 20C. Precipitated protein was collected by centrifugation at 15,000 g …

… 10/~g of each sample was subjected to electrophoresis on 0.9% agarose gels and transferred
to Nytran membranes (Schleicher & Schuell, Inc., Keene, NH). Hybridization of probes …