Infections are common in patients with rheumatic disorders. Reasons for such vulnerability
include alterations of immunoregulation, disease severity, debility, co-morbid illnesses and …

The advent of biologic agents that target proinflammatory cytokines such as interleukin-1 (IL-1)
or tumor necrosis factor alpha (TNFa) has revolutionized the understanding of the …

Recent data demonstrating the multifunctional role of serum amyloid A (SAA) in the pathogenesis
of amyloidosis have yielded important insights into this potentially fatal consequence …

… These samples were placed in nonheparinized tubes and centrifuged at 10,000g for 10
minutes. The supernatants were aliquoted and stored at −70C until further use. …

As experience with anti-tumor necrosis factor (TNF-alpha) therapy increases, there has
been the expected emergence of reports on uncommon side effects. Large clinical trials …

OBJECTIVE: Acute phase serum amyloid A (A-SAA) has been reported to be more sensitive
than C-reactive protein (CRP) as a marker of disease activity. It may function in immune …

Objective. Sleep disturbance and chronic fatigue are common in rheumatoid arthritis (RA)
and contribute to disability, symptomatology, and healthcare use. It has long been recognized …

Objective. To evaluate the effects of treatment with interleukin‐1 receptor antagonist (IL‐1Ra)
on synovial tissue in rheumatoid arthritis (RA). Methods. Twelve patients with RA entering …

Objective. The aim of this study was to explore the role of cytokines in the pathogenesis of
SLE in a genetically homogeneous Caucasian SLE patient population. Methods. Serum levels …

Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis -
Cunnane - 2001 - Arthritis & Rheumatism - Wiley Online Library … Gaye Cunnane …