Glycosaminoglycans are major constituents of the cancer cell surface and the tumor stroma.
The heparan sulfate degrading enzyme heparanase, hyaluronan, and its receptor CD44 are …

Glycosaminoglycans are unbranched polysaccharides composed of repeating units of
alternating uronic acids and amino sugars. Most glycosaminoglycans are covalently attached to …

Breast cancer pathobiology is known to be influenced by the differential expression of a group
of proteins called the kinesin superfamily (KIFs), which is instrumental in the intracellular …

Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and
developmental processes at the transcriptional and translational level. In breast cancer, miR-145 …

The heparan sulfate proteoglycan syndecan-1 (Sdc1) modulates cell proliferation, adhesion,
migration and angiogenesis. Proteinase-mediated shedding converts Sdc1 from a …

microRNAs are small endogenous noncoding RNAs, which post‐transcriptionally regulate
gene expression. In breast cancer, overexpression of the transmembrane heparan sulfate …

Objective To examine the prevalence of subclinical atherosclerosis in patients with psoriatic
arthritis (PsA) compared with healthy controls, and to identify clinical and biologic markers …

Impaired long-axis motion is a sensitive marker of systolic myocardial dysfunction, but no data
are available that relate long-axis changes in systole with those in diastole, particularly in …

The Ehlers–Danlos syndrome (EDS) is a heterogeneous group of connective tissue
disorders affecting skin and joint function. Molecular defects in extracellular matrix proteins, …

Present day strategies for delivery of wireless photodynamic therapy (PDT) to deep-seated
targets are limited by the inadequacy of irradiance and insufficient therapeutic depth. Here …