Evidence from animal models and prospective studies of RA, multiple sclerosis, and type-1
diabetes suggest an important role for vitamin D as a modifiable environmental factor in …

… Inhibiting iNOS activity in MRL/lpr mice, before disease onset, with the nonspecific arginine
analog L-N G -monomethyl-L-arginine reduced 3-nitrotyrosine formation in the kidney, …

Retroperitoneal fibrosis (RF) is a disease that can occur at any age, with a peak incidence
in patients 40 to 60 years of age. The characteristic finding in this disease is a periaortic …

… (0.5 g per square meter of body-surface area, increased to 1.0 g per square meter) as induction
therapy for active lupus nephritis. A change to the alternative regimen was allowed at 12 …

… Effect of TNF Antibody Injections on Body Weights As described in the text, TTP (/) mice from
seven litters (each litter is labeled A–G) were injected at weekly intervals starting on day 10 …

… Complete blood count at 1-month follow-up showed normal white cell count (4.7×10 9
cells/litre), haemoglobin 10.5 g/dl and an improved platelet count (95×10 9 cells/litre). …

Objective Umbilical cord (UC)–derived mesenchymal stem cells (MSCs) have shown marked
therapeutic effects in a number of diseases in animal studies, based on their potential for …

… × g for … g for 10 minutes at 4C, and the protein in the supernatants was precipitated with 1
ml of acetone overnight at 20C. Precipitated protein was collected by centrifugation at 15,000 g …

… Here, the G allele is the risk allele and creates a CpG site in the promoter region. In GTEx,
the G allele corresponds to lowest gene expression. Hence, when methylated, this variant …

In MRL mice, the mostly recessive lpr mutation results in both the accumulation of CD4-, CD8-,
CD3+ T cells in lymphoid tissue and many features of generalized autoimmune disease, …