Cell cycle-dependent gene transcription is tightly controlled by the retinoblastoma (RB):E2F
and DREAM complexes, which repress all cell cycle genes during quiescence. Cyclin-…

The precise timing of cell cycle gene expression is critical for the control of cell proliferation;
de-regulation of this timing promotes the formation of cancer and leads to defects during …

Tubulointerstitial fibrosis is an obligate finding in end-stage diseased kidneys. Renal fibrosis
is defined as excessive matrix deposition that leads to tissue destruction and impairment of …

Reports of spontaneous regressions of metastases and the demonstration of tumor-reactive
cytotoxic T lymphocytes indicate the importance of the host's immune system in controlling …

… Rodemann, HP & Müller, GA Characterization of human renal fibroblasts in health and
disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with …

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Background
Epithelial-mesenchymal transformation (EMT) plays an important role in embryonic …

Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies.
Background In recent studies performed on cultured cells and experimental nephropathies, it has …

… Strutz (DFG Str 388/3-1) and GA Müller (DFG Mü 523/7-1). M. Zeisberg was awarded a
graduate grant … Knecht, LG Fine, KS Kleinman, HP Rodemann, GA Müller, DDL Woo, JT Norman …

An improved chemiluminescence-based RNA/DNA detection procedure offering a widely
applicable alternative to the conventional 32 P labeling employed in molecular biology is …

Tubulointerstitial fibrosis is a hallmark feature of chronic renal injury. Specific therapies to
control the progression of renal fibrosis toward end-stage renal failure are limited. Previous …