Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

…, G Xie, S Eyre, BP Thomson, Y Li, FAS Kurreeman… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

…, BD Korman, L Padyukov, FAS Kurreeman… - Nature …, 2008 - nature.com
To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis
of two published genome-wide association (GWA) studies totaling 3,393 cases and …

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

…, P Kraft, R Chen, HJ Kallberg, FAS Kurreeman… - Nature …, 2012 - nature.com
The genetic architectures of common, complex diseases are largely uncharacterized. We
modeled the genetic architecture underlying genome-wide association study (GWAS) data for …

[HTML][HTML] Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

…, HJ Westra, RSN Fehrmann, FAS Kurreeman… - PLoS …, 2011 - journals.plos.org
Epidemiology and candidate gene studies indicate a shared genetic basis for celiac
disease (CD) and rheumatoid arthritis (RA), but the extent of this sharing has not been …

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

…, TWJ Huizinga, DL Kastner, X Ke, FAS Kurreeman… - Nature …, 2009 - nature.com
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P < 0.001 in a published meta-analysis of RA genome-wide …

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

…, A Suzuki, T Kawaguchi, EA Stahl, FAS Kurreeman… - Nature …, 2012 - nature.com
Rheumatoid arthritis is a common autoimmune disease characterized by chronic inflammation.
We report a meta-analysis of genome-wide association studies (GWAS) in a Japanese …

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

…, L Padyukov, FAS Kurreeman… - … : Official Journal of …, 2007 - Wiley Online Library
Objective To determine whether genetic variants of the interferon regulatory factor 5 (IRF‐5)
and Tyk‐2 genes are associated with rheumatoid arthritis (RA). Methods Five single‐…

Association of a single‐nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis

…, JJ Catanese, FAS Kurreeman… - … : Official Journal of …, 2009 - Wiley Online Library
Objective. The severity of joint destruction in rheumatoid arthritis (RA) is highly variable from
patient to patient and is influenced by genetic factors. Genome-wide association studies …

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis

NA Daha, FAS Kurreeman, RB Marques… - Arthritis & …, 2009 - Wiley Online Library
Objective Recent advances have led to novel identification of genetic polymorphisms that are
associated with susceptibility to rheumatoid arthritis (RA). Currently, 5 loci (HLA, PTPN22, …

[PDF][PDF] Use of a multiethnic approach to identify rheumatoid-arthritis-susceptibility loci, 1p36 and 17q12

FAS Kurreeman, EA Stahl, Y Okada, K Liao… - The American Journal of …, 2012 - cell.com
We have previously shown that rheumatoid arthritis (RA) risk alleles overlap between
different ethnic groups. Here, we utilize a multiethnic approach to show that we can effectively …