This paper is the first in a series of two publications relating to the European Crohn’s and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management of …

Background & Aims: Pouchitis is the major long-term complication after ileal pouch-anal
anastomosis for ulcerative colitis. Most patients have relapsing disease, and no maintenance …

BACKGROUND & AIMS:: We have recently documented the efficacy of a highly concentrated
probiotic preparation (VSL#3) in the prevention of flare-up in patients with chronic pouchitis…

Background: Ten to 15% of patients with pouchitis experience refractory or recurrent disease.
The aim of this study was to evaluate the effectiveness of a single daily high dose probiotic …

Background: “Probiotic” bacteria are effective in treating some inflammatory bowel diseases.
However which bacteria confer benefit and mechanisms of action remain poorly defined. …

The human intestinal microbiota plays a pivotal role in human nutrition and health by promoting
the supply of nutrients, preventing pathogen colonization and shaping and maintaining …

A new therapeutic approach for inflammatory bowel diseases is based on the administration
of probiotic bacteria. Prokaryotic DNA contains unmethylated CpG motifs which can activate …

Chemokines are thought to be important for the recruitment of granulocytes and mononuclear
cells and thus for the maintenance of inflammation in ulcerative colitis (UC). We have …

Background: The intestinal microbiota plays a critical role in the pathophysiology of pouchitis,
a major complication after ileal pouch anal anastomosis in patients with ulcerative colitis. …

Purpose: Pouchitis is the major long-term complication after ileal-pouch anal anastomosis for
ulcerative colitis. Broad-spectrum antibiotics are the mainstay of treatment in this condition. …