Autophagy in osteoarthritis

YS Li, FJ Zhang, C Zeng, W Luo, WF Xiao, SG Gao… - Joint Bone Spine, 2016 - Elsevier
Degradation of the articular cartilage is at the centre of the pathogenesis of osteoarthritis (OA),
for which age is the major risk factor. Maintaining the chondrocytes in a healthy condition …

Role of HIF-1α and HIF-2α in osteoarthritis

FJ Zhang, W Luo, GH Lei - Joint bone spine, 2015 - Elsevier
The hallmark of OA is cartilage destruction, several factors such as catabolic enzymes and
chondrocyte death include apoptosis and/or autophagy are considered for the pathogenesis. …

Introduction of BCC models and its participation in CMIP6

…, WU Tong-Wen, FZ Jie ZHANG… - Advances in Climate …, 2019 - climatechange.cn
Abstract: CMIP6 is being organized by the World Climate Research Project (WCRP). As one
of the institutes participating in the CMIP6, National Climate Center, China Meteorological …

Relationship between serum magnesium concentration and radiographic knee osteoarthritis

C Zeng, J Wei, H Li, T Yang, FJ Zhang, D Pan… - The Journal of …, 2015 - jrheum.org
Objective. To establish whether there is a relationship between serum magnesium (Mg)
concentration and radiographic knee osteoarthritis (OA). Methods. There were 2855 subjects in …

Correlation between senescence‐associated beta‐galactosidase expression in articular cartilage and disease severity of patients with knee osteoarthritis

SG Gao, C Zeng, LJ Li, W Luo, FJ Zhang… - … journal of rheumatic …, 2016 - Wiley Online Library
Aim The purposes of this study were to investigate senescence‐associated beta‐galactosidase
( SA ‐beta‐ G al) levels in articular cartilage of knee osteoarthritis ( OA ) and the …

Role of integrins and their ligands in osteoarthritic cartilage

J Tian, FJ Zhang, GH Lei - Rheumatology international, 2015 - Springer
Osteoarthritis (OA) is a degenerative disease, which is characterized by articular cartilage
destruction, and mainly affects the older people. The extracellular matrix (ECM) provides a …

[HTML][HTML] Osteopontin, a bridge links osteoarthritis and osteoporosis

RJ Bai, YS Li, FJ Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease characterized by degradation of
articular cartilage, inflammation, and changes in periarticular and subchondral bone of joints. …

Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase

…, AS Zhou, JA Jernelius, FJ Zhang… - Journal of medicinal …, 2008 - ACS Publications
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are recommended components of
preferred combination antiretroviral therapies used for the treatment of HIV. These regimens …

Prognostic significance of plasma chemerin levels in patients with gastric cancer

J Zhang, HC Jin, AK Zhu, RC Ying, W Wei, FJ Zhang - Peptides, 2014 - Elsevier
Chemerin is a novel adipokine, which is linked to adipogenesis and chemotaxis of the
innate immune system. This study aimed to evaluate the relationship between preoperative …

The effect of hyaluronic acid on osteopontin and CD44 mRNA of fibroblast-like synoviocytes in patients with osteoarthritis of the knee

FJ Zhang, SG Gao, L Cheng, J Tian, WS Xu… - Rheumatology …, 2013 - Springer
The aim of this study was to investigate the effect of hyaluronic acid (HA) on the expression
of osteopontin (OPN) and CD44 mRNA of fibroblast-like synoviocytes (FLS) in the patients …