Juvenile Localized Scleroderma (JLS) is a rare disorder that may cause severe aesthetic
sequelae and functional disability. To date, data on natural history and long-term outcome are …

Objective Juvenile localized scleroderma is a chronic progressive fibrotic disorder of the
skin that causes permanent disability and aesthetic damage. This study was undertaken to …

The aim of the study was to evaluate the immunohistochemical expression of p16 INK4a as
a marker of progression risk in low-grade dysplastic lesions of the cervix uteri. p16 INK4a …

Objective. To evaluate safety and efficacy of adalimumab (ADA) and infliximab (IFX) for the
treatment of juvenile idiopathic arthritis-related anterior uveitis (JIA-AU). Methods. Starting …

It is estimated that around 20% of patients with systemic lupus erythematosus (SLE) have their
onset in childhood but there have been conflicting data about the prevalence and severity …

Background Recent studies report that methotrexate (MTX) is beneficial in the treatment of
juvenile localized scleroderma (JLS) but little is known about its long-term effectiveness. …

Background The EUROCARE-5 study revealed disparities in childhood cancer survival among
European countries, giving rise to important initiatives across Europe to reduce the gap. …

Background: Most of the available documentation in the literature on ocular involvement in
localised scleroderma (LS) are descriptions of single cases in adult patients. This article …

As only a minority of low-grade dysplastic lesions of the cervix uteri will eventually progress
to carcinoma, predicting the behavior of these lesions could be of high value in clinical …

Objective. Anti-TNF-α agents have significantly changed the management of juvenile idiopathic
arthritis (JIA). We evaluated the safety and efficacy of adalimumab (ADA) and infliximab (…