Objectives Treat-to-target recommendations have identified ‘remission’ as a target in systemic
lupus erythematosus (SLE), but recognise that there is no universally accepted definition …

SLE is an autoimmune condition characterized by loss of tolerance to chromatin constituents
and the production of ANAs. The majority of SLE patients display spontaneous expression …

Systemic sclerosis (SSc) is an orphan disease characterised by autoimmunity, fibrosis of the
skin and internal organs, and vasculopathy. SSc may be associated with high morbidity and …

Objective To analyze the clinical and immunologic manifestations of antiphospholipid
syndrome (APS) in a large cohort of patients and to define patterns of disease expression. …

In the present study, we assessed the frequency and characteristics of the main causes of
morbidity and mortality in systemic lupus erythematosus (SLE) during a 10-year period and …

Objective Glomerulonephritis is a severe manifestation of systemic lupus erythematosus (SLE)
that is usually treated with an extended course of intravenous (IV) cyclophosphamide (…

Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

Systemic Lupus Erythematosus: Clinical and Immunologic Patte... : Medicine Systemic Lupus
Erythematosus: Clinical and Immunologic Patterns of Disease Expression in a Cohort of …

Objectives To develop recommendations for the management of adult and paediatric lupus
nephritis (LN). Methods The available evidence was systematically reviewed using the …

Interleukin‐6 (IL‐6), also called 26‐kd protein, hybridoma plasmacytoma growth factor, β 2 ‐interferon,
or B cell stimulatory factor 2, is a recently described human cytokine with multiple …