In December 2019, a new and highly contagious infectious disease emerged in Wuhan,
China. The etiologic agent was identified as a novel coronavirus, now known as Severe Acute …

COVID-19 (Coronavirus Disease 2019) is a highly contagious infection and associated with
high mortality rates, primarily in elderly; patients with heart failure; high blood pressure; …

Calcium (Ca 2+ ) is an important cation able to function as a second messenger in different
cells of the immune system, particularly in B and T lymphocytes, macrophages, and …

Aim The aim of this study was to describe a case series of patients with primary or secondary
antiphospholipid syndrome (APS) treated with direct oral anticoagulants (DOACs). Patients …

Purpose The aim of this study was to describe the efficacy and safety of anti–interleukin 6
receptor antibody (tocilizumab [TCZ]) in patients with severe or refractory Takayasu arteritis (TA…

Autoimmune diseases (AIDs) are chronic conditions initiated by the loss of immunological
tolerance to self-antigens and represent a heterogeneous group of disorders that affect …

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss
syndrome (CSS), is a small vessel vasculitis associated with eosinophilia and asthma. Clinical …

El calcio (Ca2+) es un catión con capacidad multifuncional como segundo mensajero en
diferentes grupos celulares del sistema inmunitario que incluyen los linfocitos T y B, los …

New cases of Pneumocystis jirovecii pneumonia (PJP) have recently been reported in
patients with systemic lupus erythematosus (SLE) after rituximab therapy. Several factors may …

We report a female patient with rheumatoid arthritis which was refractory to methotrexate,
leflunomide, and anti-TNF therapy. She was treated with anti-IL-6 tocilizumab (TCZ), with an …