Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA),
and primary Sjögren's syndrome (pSS) are complex disorders with a genetic background …

IL-23 is a pro-inflammatory cytokine belonging to the IL-12 cytokine family. IL-23 is essential
for the differentiation of Th17 lymphocytes, a subtype of T lymphocyte implicated in chronic …

Paradoxical adverse events (PAEs) have been reported during biological treatment for chronic
immune-mediated diseases. PAEs are defined as the occurrence during biological agent …

OBJECTIVES: To describe cases of new onset of inflammatory bowel disease (IBD) in patients
with inflammatory rheumatic disease (IRD) receiving anti-TNF-α therapy. METHODS: A …

Objective. TNF blockers have been recently evaluated for treating refractory sarcoidosis and
could be efficient. However, several cases of sarcoidosis have been diagnosed during anti-…

Objective. We describe myelodysplastic syndrome (MDS)–associated systemic inflammatory
and autoimmune diseases (SIADs), their treatments and outcomes and the impact of SIADs …

Adipokines are proteins produced by white adipose tissue, which is an active secretory organ.
Regulation of immune and inflammatory responses is among the multiple physiological …

To define the clinical and immunologic pattern of expression of Sjögren syndrome (SS)
associated with chronic hepatitis C virus (HCV) infection, we conducted a multicenter study …

Adipokines such as leptin and adiponectin are involved in the regulation of inflammation.
Ghrelin, a gastric peptide playing a role in the appetite regulation, possesses anti-inflammatory …

Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …