Background Biologics are used for the treatment of rheumatoid arthritis and many other
conditions. While the efficacy of biologics has been established, there is uncertainty regarding …

Background Serious infections are a major concern for patients considering treatments for
rheumatoid arthritis. Evidence is inconsistent as to whether biological drugs are associated …

Background The biologic disease‐modifying anti‐rheumatic drugs (DMARDs) are very
effective in treating rheumatoid arthritis (RA), however there is a lack of head‐to‐head …

Background Methotrexate (MTX) is a disease modifying antirheumatic drug (DMARD) used
as a first line agent for treating rheumatoid arthritis (RA). Pharmacologically, it is classified as …

Background: We sought to compare the benefits and safety of 6 biologics (abatacept,
adalimumab, anakinra, etanercept, infliximab and rituximab) in patients with rheumatoid arthritis. …

Background TNF (tumor necrosis factor)‐alpha inhibitors block a key protein in the
inflammatory chain reaction responsible for joint inflammation, pain, and damage in ankylosing …

Objective. To perform a systematic review of the benefits and harms of folic acid and folinic
acid in reducing the mucosal, gastrointestinal, hepatic, and hematologic side effects of …

The Cochrane Musculoskeletal Group (CMSG), one of 53 groups of the not-for-profit, international
Cochrane Collaboration, prepares, maintains, and disseminates systematic reviews of …

Background Soil-transmitted helminthiasis and schistosomiasis, considered among the
neglected tropical diseases by WHO, affect more than a third of the world's population, with …

Background Enhancing health equity is endorsed in the Sustainable Development Goals.
The failure of systematic reviews to consider potential differences in effects across equity …