Hereditary hypouricemia may result from mutations in the renal tubular uric acid transporter
URAT1. Whether mutation of other uric acid transporters produces a similar phenotype is …

A heterotrimeric G alpha i subunit, alpha i-3, is localized on Golgi membranes in LLC-PK1
and NRK epithelial cells where it colocalizes with mannosidase II by immunofluorescence. …

Genomic clones including the 5' flanking regions of the AQP2 (aquaporin 2) gene were
isolated, and the promoter region was examined by transiently transfecting a promoter-luciferase …

Familial hyperkalemia and hypertension (FHH; pseudohypoaldosteronism type II) is an
autosomal dominant disorder characterized by hyperkalemia, hypertension, and low renin. …

Context: The risk associated with serum uric acid (SUA) levels within the normal range is
unknown, especially among lean and apparently healthy adults. Objective: Evaluating whether …

There are data describing that cardiovascular risks related to serum uric acid (SUA) levels
may begin below the current diagnostic level for hyperuricemia. Values from 5.2 to 6.0 mg/dL …

Background . Hereditary renal hypouricemia may be complicated by nephrolithiasis or
exercise-induced acute renal failure. Most patients described so far are of Japanese origin and …

Eur J Clin Invest 2011; 41 (10): 1113–1120 Abstract Background Cyclosporine is used for
treatment of transplanted patients and for immune‐mediated diseases. Cyclosporine is known …

Background. Elevated serum uric acid (UA) is associated with gout, hypertension,
cardiovascular and renal disease. Hereditary renal hypouricemia type 1 (RHUC1) is caused by …

A recently presented hypothesis contends that the excess coronary heart disease mortality
associated with hypertension is more prominent in lean men than in overweight men. This …