Objective To develop new classification criteria for systemic lupus erythematosus ( SLE )
jointly supported by the European League Against Rheumatism ( EULAR ) and the American …

In addition to their pivotal role in thrombosis and wound repair, platelets participate in
inflammatory responses. We investigated the role of platelets in the autoimmune disease …

CD4 + T cells are central mediators of autoimmune pathology; however, defining their key
effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4 + T …

Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is
ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed …

Context Rheumatoid arthritis (RA) and psoriasis have been linked with insulin resistance
and diabetes mellitus (DM). Prior investigations suggest that systemic immunosuppressive …

Objective This study was undertaken to investigate whether recent advances in lupus
nephritis treatment have led to changes in the incidence of end‐stage renal disease (ESRD) …

The 25-item Work Limitations Questionnaire (WLQ) was recently developed to measure
health-related decrements in ability to perform job roles among employed individuals. Research …

Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic
citrullinated peptide (anti‐CCP) and rheumatoid factor (RF) autoantibodies in …

Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome of uncontrolled immune
activation that has gained increasing attention during the last decade. The diagnosis of HLH is …

Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disorder
characterized by symmetric inflammation of synovial joints leading to progressive erosion of …