User profiles for EMILY C. BAECHLER
 | Emily C BaechlerAssistant Professor, University of Minnesota Verified email at umn.edu Cited by 11120 |
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
EC Baechler, FM Batliwalla, G Karypis… - Proceedings of the …, 2003 - National Acad Sciences
Systemic lupus erythematosus (SLE) is a complex, inflammatory autoimmune disease that
affects multiple organ systems. We used global gene expression profiling of peripheral blood …
affects multiple organ systems. We used global gene expression profiling of peripheral blood …
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
…, AA Bengtsson, S Rantapää-Dahlqvist, EC Baechler… - Nature …, 2009 - nature.com
Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …
[PDF][PDF] Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
…, VEH Carlton, M Chang, P Ramos, EC Baechler… - The American Journal of …, 2004 - cell.com
We genotyped 525 independent North American white individuals with systemic lupus
erythematosus (SLE) for the PTPN22 R620W polymorphism and compared the results with data …
erythematosus (SLE) for the PTPN22 R620W polymorphism and compared the results with data …
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
RR Graham, SV Kozyrev, EC Baechler, MVPL Reddy… - Nature …, 2006 - nature.com
Systemic lupus erythematosus (SLE) is a complex autoimmune disease 1 characterized by
activation of the type I interferon (IFN) pathway 2 , 3 , 4 . Here we convincingly replicate …
activation of the type I interferon (IFN) pathway 2 , 3 , 4 . Here we convincingly replicate …
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
…, LRL Davies, EC Baechler… - Proceedings of the …, 2007 - National Acad Sciences
Systematic genome-wide studies to map genomic regions associated with human diseases
are becoming more practical. Increasingly, efforts will be focused on the identification of the …
are becoming more practical. Increasingly, efforts will be focused on the identification of the …
[HTML][HTML] Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus
JW Bauer, EC Baechler, M Petri, FM Batliwalla… - PLoS …, 2006 - journals.plos.org
Background Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder
that affects multiple organ systems and is characterized by unpredictable flares of disease. …
that affects multiple organ systems and is characterized by unpredictable flares of disease. …
Interferon‐regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study
…, TW Behrens, EC Baechler - … : Official Journal of …, 2009 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized
by unpredictable flares of disease activity and irreversible damage to multiple organ …
by unpredictable flares of disease activity and irreversible damage to multiple organ …
[HTML][HTML] An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity
EC Baechler, JW Bauer, CA Slattery, WA Ortmann… - Molecular …, 2007 - Springer
Recent studies have shown increased expression of interferon (IFN)-regulated genes in the
peripheral blood cells of patients with systemic lupus erythematosus. A similar interferon …
peripheral blood cells of patients with systemic lupus erythematosus. A similar interferon …
Peripheral blood gene expression profiling in Sjögren's syndrome
…, JM Leon, CJ Lessard, M Grandits, EC Baechler… - Genes & …, 2009 - nature.com
Sjögren's syndrome (SS) is a common chronic autoimmune disease characterized by
lymphocytic infiltration of exocrine glands. The affected cases commonly present with oral and …
lymphocytic infiltration of exocrine glands. The affected cases commonly present with oral and …
Interleukin‐6 and type I interferon–regulated genes and chemokines mark disease activity in dermatomyositis
…, JW Bauer, EJ Peterson, EC Baechler… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Up‐regulation of whole blood type I interferon (IFN)–driven transcripts and
chemokines has been described in a number of autoimmune diseases. An IFN gene expression “…
chemokines has been described in a number of autoimmune diseases. An IFN gene expression “…