Osteoid osteoma and osteoblastoma present a challenge to the clinician in both diagnosis
and management. It is important to recognize their clinical presentation to make an early …

Although there have been a few large case series of giant cell tumor (GCT) in the spine and
sacrum, the treatment of these lesions remains controversial. We are reporting 23 additional …

Objective: To determine factors including treatment modalities which influence survival in
patients with osteosarcoma of the head and neck. Study Design: Retrospective …

In 1891, William B. Coley injected streptococcal organisms into a patient with inoperable
cancer. He thought that the infection he produced would have the side effect of shrinking the …

Objective To gain a broader appreciation of the clinical presentation, operative treatment,
and outcome of patients with fibrous dysplasia involving the skull base. Design Retrospective …

Axial chordoma represents approximately 1% of malignant bone tumors. This tumor expresses
cytokeratins, specifically cytokeratin 19, and commonly S100. More recently brachyury, a …

Oncogenic osteomalacia, an acquired hypophosphataemic syndrome associated with
mesenchymal tumours, is characterised by hypophosphataemia secondary to inappropriate …

Object Chordoma is a malignant bone neoplasm hypothesized to arise from notochordal
remnants along the length of the neuraxis. Recent genomic investigation of chordomas has …

Bone regeneration following injury is initiated by inflammatory signals and occurs in
association with infiltration by sensory nerve fibers. Together, these events are believed to …

Objective The objective was to characterize imaging findings of benign notochordal cell
tumors (BNCTs). Design and patients Clinical and imaging data for 9 benign notochordal cell …