Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
… We also compared TadA-8a-e variants with TadA-7.10 for levels of A•T-to-G•C base editing
when tethered to catalytically dead LbCas12a (dLbCas12a). Unlike Cas9 homologs, Cas12a …
when tethered to catalytically dead LbCas12a (dLbCas12a). Unlike Cas9 homologs, Cas12a …
Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database
…, E Ton, G Kumánovics, B Coleiro, E Feierl… - Annals of the …, 2010 - ard.bmj.com
Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc).
Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria …
Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria …
Empathy as a “risky strength”: A multilevel examination of empathy and risk for internalizing disorders
… ) found that attachment style interacted with vagal tone, which provides an index of emotion
… lowest among youths with high levels of attachment insecurity and low levels of vagal tone. …
… lowest among youths with high levels of attachment insecurity and low levels of vagal tone. …
Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: a randomized trial
…, SMM Verstappen, J Tekstra, E Ton… - Annals of internal …, 2012 - acpjournals.org
Background: Treatment strategies for tight control of early rheumatoid arthritis (RA) are highly
effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/…
effective but can be improved. Objective: To investigate whether adding prednisone, 10 mg/…
[HTML][HTML] Chimpanzee accumulative stone throwing
…, S Jones, L Kehoe, S Regnaut, A Tickle, E Ton… - Scientific Reports, 2016 - nature.com
The study of the archaeological remains of fossil hominins must rely on reconstructions to
elucidate the behaviour that may have resulted in particular stone tools and their accumulation…
elucidate the behaviour that may have resulted in particular stone tools and their accumulation…
Pulmonary embolism: validation of spiral CT angiography in 149 patients.
AB van Rossum, PM Pattynama, ER Ton, FE Treurniet… - Radiology, 1996 - pubs.rsna.org
PURPOSE: To assess the reliability of spiral computed tomographic (CT) angiography of
the pulmonary arteries in the diagnosis of pulmonary embolism (PE). MATERIALS AND …
the pulmonary arteries in the diagnosis of pulmonary embolism (PE). MATERIALS AND …
Risk factors for pelvic pouch failure
…, Z Cohen, BI O'Connor, ENC Ton - Diseases of the colon …, 1997 - journals.lww.com
PURPOSE: This study was designed to identify factors associated with pelvic pouch failure.
METHOD: A retrospective review of patients undergoing the pelvic pouch procedure with a …
METHOD: A retrospective review of patients undergoing the pelvic pouch procedure with a …
Neural responses to peer rejection in anxious adolescents: contributions from the amygdala-hippocampal complex
Peer rejection powerfully predicts adolescent anxiety. While cognitive differences influence
anxious responses to social feedback, little is known about neural contributions. Twelve …
anxious responses to social feedback, little is known about neural contributions. Twelve …
Systemic sclerosis and its pulmonary complications in The Netherlands: an epidemiological study
MC Vonk, B Broers, YF Heijdra, E Ton… - Annals of the …, 2009 - ard.bmj.com
The prevalence and incidence of systemic sclerosis (SSc) in The Netherlands is unknown.
The same holds true for its leading causes of death: pulmonary fibrosis and pulmonary …
The same holds true for its leading causes of death: pulmonary fibrosis and pulmonary …
The network structure of schizotypal personality traits
Elucidating schizotypal traits is important if we are to understand the various manifestations
of psychosis spectrum liability and to reliably identify individuals at high risk for psychosis. …
of psychosis spectrum liability and to reliably identify individuals at high risk for psychosis. …