Global epidemiology of systemic lupus erythematosus

…, A Hoi, A Mak, NY Kow, E Svenungsson… - Nature Reviews …, 2021 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with protean manifestations
that predominantly affects young women. Certain ethnic groups are more vulnerable than …

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

…, M Schneider, JS Smolen, E Svenungsson… - Annals of the …, 2019 - ard.bmj.com
Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

…, G Nordmark, I Gunnarsson, E Svenungsson… - Nature …, 2009 - nature.com
Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

…, G Gröndal, AI Bolstad, E Svenungsson… - Nature …, 2002 - nature.com
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that
affects 0.05% of the Western population, predominantly women 1, 2, 3, 4. A number of …

Prevention of cardiovascular disease in rheumatoid arthritis

…, PH Dessein, N Ronda, MC Wasko, E Svenungsson… - Autoimmunity …, 2015 - Elsevier
The increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) has been
recognized for many years. However, although the characteristics of CVD and its burden …

[HTML][HTML] EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with …

…, L Raio, M Schneider, E Svenungsson… - Annals of the …, 2017 - ard.bmj.com
Objectives Develop recommendations for women9s health issues and family planning in
systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS). Methods …

Impact of glucocorticoids on the incidence of lupus-related major organ damage: a systematic literature review and meta-regression analysis of longitudinal …

…, E Svenungsson, M Urowitz, E Vinet… - Lupus science & …, 2021 - lupus.bmj.com
Objective In systemic lupus erythematosus (SLE), disease activity and glucocorticoid (GC)
exposure are known to contribute to irreversible organ damage. We aimed to examine the …

EULAR recommendations for the management of antiphospholipid syndrome in adults

…, Y Shoenfeld, L Stojanovich, E Svenungsson… - Annals of the …, 2019 - ard.bmj.com
The objective was to develop evidence-based recommendations for the management of
antiphospholipid syndrome (APS) in adults. Based on evidence from a systematic literature …

Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus

…, E Sanchez, I Gunnarsson, E Svenungsson… - Nature …, 2008 - nature.com
Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by
production of autoantibodies and complex genetic inheritance 1 , 2 , 3 . In a genome-wide …

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

…, I Gunnarsson, E Svenungsson… - Proceedings of the …, 2007 - National Acad Sciences
Systematic genome-wide studies to map genomic regions associated with human diseases
are becoming more practical. Increasingly, efforts will be focused on the identification of the …