Influencing the tumor microenvironment: a phase II study of copper depletion using tetrathiomolybdate in patients with breast cancer at high risk for recurrence and in …
…, MM Ward, SB Lee, E Nackos, BR Seo, E Chuang… - Clinical Cancer …, 2017 - AACR
Purpose: Bone marrow–derived progenitor cells, including VEGFR2 + endothelial progenitor
cells (EPCs) and copper-dependent pathways, model the tumor microenvironment. We …
cells (EPCs) and copper-dependent pathways, model the tumor microenvironment. We …
Microtubule inhibitor-based antibody–drug conjugates for cancer therapy
K Klute, E Nackos, S Tasaki, DP Nguyen… - OncoTargets and …, 2014 - Taylor & Francis
The specificity of monoclonal antibodies represents a potential therapeutic advantage, but
their use as single agents in oncology has proven limited to date. The development of …
their use as single agents in oncology has proven limited to date. The development of …
Homocysteine levels and disease duration independently correlate with coronary artery calcification in patients with systemic lupus erythematosus
…, E Nackos, A Chander, E Gehrie… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To compare the incidence and extent of coronary artery calcification (CAC) as
measured by electron beam computed tomography (EBCT) in patients with systemic lupus …
measured by electron beam computed tomography (EBCT) in patients with systemic lupus …
Resistin levels in lupus and associations with disease-specific measures, insulin resistance, and coronary calcification
…, M Qatanani, A Cucchiara, E Nackos… - The Journal of …, 2011 - jrheum.org
Objective. To evaluate levels of resistin in female subjects with systemic lupus erythematosus
(SLE) compared to age and race-matched controls and to determine the relationship …
(SLE) compared to age and race-matched controls and to determine the relationship …
Monocyte chemoattractant protein-1: plasma concentrations and A (-2518) G promoter polymorphism of its gene in systemic lupus erythematosus.
KS Brown, E Nackos, S Morthala, LE Jensen… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To determine (1) whether the A(-2518)G polymorphism of CCL-2, the gene
encoding monocyte chemoattractant protein-1 (MCP-1), is associated with disease, MCP-1 …
encoding monocyte chemoattractant protein-1 (MCP-1), is associated with disease, MCP-1 …
Functional polymorphisms of folate-metabolizing enzymes in relation to homocysteine concentrations in systemic lupus erythematosus
…, E Nackos, AL Hammons, E Mohr… - The Journal of …, 2008 - jrheum.org
Objective To determine if functional polymorphisms of folate/homocysteine pathway enzymes
are associated with homocysteine concentrations and/or coronary artery calcification (CAC…
are associated with homocysteine concentrations and/or coronary artery calcification (CAC…
Correction: influencing the tumor microenvironment: a phase II study of copper depletion using tetrathiomolybdate in patients with breast cancer at high risk for …
…, MM Ward, SB Lee, E Nackos, BR Seo, E Chuang… - Clinical Cancer …, 2020 - AACR
In the original version of this article (1), the abstract contained an incorrect value for eventfree
survival in stage IV NED patients with triple-negative breast cancer. The value (69%) was …
survival in stage IV NED patients with triple-negative breast cancer. The value (69%) was …
Altering the tumor microenvironment: A phase II study of copper depletion using tetrathiomolybdate (TM) in patients (pts) with breast cancer (BC) at high risk for …
EN Nackos, N Kornhauser, MM Ward, T Cigler… - 2015 - ascopubs.org
11008 Background: Bone marrow derived endothelial progenitor cells (EPCs) and copper-dependent
pathways are critical components to remodeling the tumor microenvironment and …
pathways are critical components to remodeling the tumor microenvironment and …
Abstract LB-349: Copper depletion as a strategy to affect the tumor microenvironment in breast cancer patients at high risk of relapse and in triple negative preclinical …
E Nackos, S Lee, A Willis, N Kornhauser, M Ward… - Cancer Research, 2016 - AACR
Background: The pre-metastatic niche mobilizes copper to assist in conditioning the tumor
microenvironment facilitating tumor progression. This includes bone marrow derived VEGFR2…
microenvironment facilitating tumor progression. This includes bone marrow derived VEGFR2…
Abstract P3-02-02: Targeting the tumor microenvironment: A phase II study of copper-depletion using tetrathiomolybdate (TM) in patients (pts) with breast cancer (BC) …
E Nackos, A Willis, N Kornhauser, M Ward… - Cancer Research, 2016 - AACR
Background: Bone marrow derived VEGFR2+ endothelial progenitor cells (EPCs) and
copper-dependent pathways, including lysyl oxidase (LOX), are critical components to remodeling …
copper-dependent pathways, including lysyl oxidase (LOX), are critical components to remodeling …