[HTML][HTML] Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity

…, EJ Bennink, C Frielink, LWJ Toonen… - British journal of …, 2006 - nature.com
Dendritic cells (DC) are professional antigen-presenting cells that play a pivotal role in the
induction of immunity. Ex vivo-generated, tumour antigen-loaded mature DC are currently …

[HTML][HTML] Successful treatment of COVID-19 with remdesivir in the absence of humoral immunity

…, L Bergamaschi, L Turner, F Mescia, EJ Toonen… - 2020 - europepmc.org
The response to the coronavirus disease 2019 (COVID-19) pandemic has been hampered
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] The binarity of the local white dwarf population

S Toonen, M Hollands, BT Gänsicke… - Astronomy & …, 2017 - aanda.org
Context. As endpoints of stellar evolution, white dwarfs (WDs) are powerful tools to study the
evolutionary history of the Galaxy. In particular, the multiplicity of WDs contains information …

IL-1 family cytokine pathways underlying NAFLD: towards new treatment strategies

…, T Chavakis, LAB Joosten, EJM Toonen - Trends in molecular …, 2018 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide.
Pathways responsible for the activation of IL-1 family cytokines are key in the development of …

[HTML][HTML] Toll-like receptor 2 controls expansion and function of regulatory T cells

…, M Kramer, EJ Bennink, LWJ Toonen… - The Journal of …, 2006 - Am Soc Clin Investig
Tregs play a central role in the suppression of immune reactions and prevention of autoimmune
responses harmful to the host. During acute infection, however, Tregs might hinder …

Complement activation in the disease course of coronavirus disease 2019 and its effects on clinical outcomes

…, EJM Toonen… - The Journal of …, 2021 - academic.oup.com
Background Excessive activation of immune responses in coronavirus disease 2019 (COVID-19)
is considered to be related to disease severity, complications, and mortality rate. The …

Synergy between In situ Cryoablation and TLR9 Stimulation Results in a Highly Effective In vivo Dendritic Cell Vaccine

…, RPM Sutmuller, S Nierkens, EJ Bennink, LWJ Toonen… - Cancer research, 2006 - AACR
Dendritic cells (DC) are professional antigen-presenting cells that play a pivotal role in the
induction of immunity. Ex vivo–generated, tumor antigen–loaded mature DC are currently …

Arrests of women for driving under the influence.

ER Shore, ML McCoy, LA Toonen, EJ Kuntz - Journal of studies on …, 1988 - jsad.com
Police records of arrests of women in Wichita, Kansas for driving under the influence (DUI)
of alcohol for a 5-year period (1980-1984) were studied. The proportion of arrests of women …

Fast-rising blue optical transients and AT2018cow following electron-capture collapse of merged white dwarfs

M Lyutikov, S Toonen - Monthly Notices of the Royal …, 2019 - academic.oup.com
We suggest that fast-rising blue optical transients (FBOTs) and the brightest event of the
class, AT2018cow, result from an electron-capture collapse to a neutron star following the …

Massive runaway and walkaway stars-A study of the kinematical imprints of the physical processes governing the evolution and explosion of their binary progenitors

…, S Justham, RJ Farmer, RG Izzard, S Toonen… - Astronomy & …, 2019 - aanda.org
… assumes instantaneous loss of the ejecta, because the ejecta velocity v ej is much larger
than the orbital velocity v orb (v orb ≲ 10 2 km s −1 ≪ v ej ∼ 10 4 km s −1 ). This algorithm …